คณะแพทยศาสตร์ มหาวิทยาลัยสยาม
อาคาร เฉลิมพระเกียรติ 19 ชั้น 14
เลขที่ 38 ถนน เพชรเกษม แขวงบางหว้า เขตภาษีเจริญ กรุงเทพฯ 10160
Tel: 02-868-6000 ต่อ 5408 Fax: 02-868-6832 Email: med@siam.edu
Website : https://med.siam.edu/
Title : Reference value of Forced Oscillation Technique for healthy preschool children
Researcher : Clin.Prof.Suwat Benjaponpitak
Department : Faculty of Medicine, Siam University, Bangkok, Thailand
E-mail : med@siam.edu
Abstract : Background: The reference values of Forced Oscillation Technique (FOT) parameters of the inspiratory and expiratory phase for preschool children have not yet been established.
Objective: To evaluate FOT measures in Thai healthy preschool children.
Methods: Preschool children, aged 3-6 years, were screened. Children who were positive for the International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire for asthma, positive family history of allergic diseases, recent lower respiratory tract infections, and environmental tobacco smoke were excluded. FOT parameters, including resistance (Rrs), reactance (Xrs), frequency of resonance (Fres) and area of reactance (ALX), were measured.
Results: A total of 390 healthy children with the mean age of 5.1 ± 0.9 years were enrolled. FOT was successfully performed in 378 children (96.9%). The mean (SD) for the whole breath (WB) resistance at 5Hz (R5), 20 Hz (R20) and R5-20 were 11.49 (2.69) cmH2O/L/s, 9.46 (2.19) cmH2O/L/s and 2.02 (0.82) cmH2O/L/s, respectively. The median (IQR) for WB reactance at 5Hx (X5), Fres and ALX were -1.51 (-2.37 to -0.96) cmH2O/L/s, 11.17 (8.50-15.65) Hz, and 7.53 (3.72-14.32) cmH2O/L/s, respectively. Significantly difference in WB R5, R20, X5, Fres and ALX between male and female children were demonstrated. The expiratory phase R5, R20, R5-20 were significantly higher than those of the inspiratory phase (p < 0.001). There are significant correlations between the height and FOT parameters. Reference curve for the FOT parameters was generated based on height using the lambda-mu-sigma (LMS) method.
Conclusion: Reference curve of FOT parameters measured in healthy preschool children were demonstrated. Majority of preschool children could perform FOT method.
Key words: Respiratory resistance, Respiratory reactance, LMS method, Frequency of resonance, Area of reactance
Link to article : Asian Pacific Journal of Allergy and Immunology, 2021, 39(2), pp. 89–95. DOI: 10.12932/AP-110618-0334
Journal : Asian Pacific journal of allergy and immunology / in Scopus
Bibliography : Mukdjindapa, P., Manuyakorn, W., Kiewngam, P., Sasisakulporn, C., Pongchaikul, P., Kamchaisatian, W., & Benjaponpitak, S. (2021). Reference value of Forced Oscillation Technique for healthy preschool children. Asian Pac J Allergy Immunol, 39(2), 89–95. doi: 10.12932/AP-110618-0334. Epub ahead of print. PMID: 30525741.
คณะแพทยศาสตร์ มหาวิทยาลัยสยาม
อาคาร เฉลิมพระเกียรติ 19 ชั้น 14
เลขที่ 38 ถนน เพชรเกษม แขวงบางหว้า เขตภาษีเจริญ กรุงเทพฯ 10160
Tel: 02-868-6000 ต่อ 5408 Fax: 02-868-6832 Email: med@siam.edu
Website : https://med.siam.edu/