Prevalence and antimicrobial susceptibility of methicillinresistant Staphylococcus aureus clones: A study at Taksin Hospital, Bangkok, Thailand (2022)

Title           : Prevalence and antimicrobial susceptibility of methicillinresistant Staphylococcus aureus clones: A study at Taksin Hospital, Bangkok, Thailand 

Researcher       : Chanwit Tribuddharata, Chalermsri Pummangurab, Maytinee Srifuengfunga, Piyawan Pipobwatthanac, Huttaya Thuncharoonc, Vipavee Rodjunb, Piriyaporn Chongtrakoola, Somporn Srifuengfung

Link to article: ScienceAsia , Volume 48, Issue 2, 2022, Pages 159-164 | https://www.scienceasia.org/content/viewabstract_progress.php?ms=12835


Journal : ScienceAsia  / Scopus


Citation : Tribuddharata C., Pummangurab C., Srifuengfunga M., Pipobwatthanac P., Thuncharoonc H., Rodjunb V., Chongtrakoola P., Srifuengfung S. (2022). Prevalence and antimicrobial susceptibility of methicillinresistant Staphylococcus aureus clones: A study at Taksin Hospital, Bangkok, Thailand. ScienceAsia, 48(2), 159-164.


ฐานข้อมูลงานวิจัย มหาวิทยาลัยสยาม            :  https://e-research.siam.edu/kb/prevalence-and-antimicrobial-susceptibility/

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Prevalence and Antimicrobial Susceptibility of Streptococcus pneumoniae Isolated from Hospital in Thailand between 2016 and 2020 (2022)

Title           :  Prevalence and Antimicrobial Susceptibility of Streptococcus pneumoniae Isolated from Hospital in Thailand between 2016 and 2020

Researcher       : Piriyaporn Chongtrakool, Yukol Aphiyakul, Patcharee Choochur, Chalermsri Pummangura, Maytinee Srifuengfung, Apichote So-Ngern, Ruxjinda Wattanalai, Somporn Srifuengfung

Link to article : Journal of the Medical Association of Thailand, Volume 105, Issue 2, 2022, Pages 113-120. http://www.jmatonline.com/index.php/jmat/article/view/13266


Journal :  Journal of the Medical Association of Thailand / Scopus


Citation : Chongtrakool P.Aphiyakul Y.Choochur P.Pummangura C.Srifuengfung M.So-Ngern A.Wattanalai R.Srifuengfung S. (2022). Prevalence and antimicrobial susceptibility of streptococcus pneumoniae isolated from hospital in Thailand between 2016 and 2020. Journal of the Medical Association of Thailand, 105(2), 113-120.


ฐานข้อมูลงานวิจัย มหาวิทยาลัยสยาม            :  https://e-research.siam.edu/kb/prevalence-and-antimicrobial/

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Prevalence and factors associated with COVID-19 among healthcare workers at a university hospital in Thailand (2022)

Title           : Prevalence and factors associated with COVID-19 among healthcare workers at a university hospital in Thailand

Researcher       : Sirijatuphat, R.Leelarasamee, A.Horthongkham, N.

Abstract            :  Globally, healthcare workers (HCWs) have a high risk of SARS-CoV-2 infection, but less is known about healthcare workers in Thailand. We estimated the prevalence and risk factors for COVID-19 among HCWs in Bangkok, Thailand. A retrospective cohort study was conducted at a large tertiary care academic hospital in Thailand from May 2020 to May 2021. HCWs that presented with fever and/or acute respiratory tract symptoms who tested with RT-PCR were identified, and their clinical data were collected. There were 1432 HCWs with fever and/or acute respiratory tract symptoms during May 2020 and May 2021. A total of 167 patients were front-line HCWs and 1265 were non-front-line HCWs. Sixty HCWs (4.2%) developed COVID-19; 2 were front-line and 58 were non-front-line HCWs. The prevalence of COVID-19 in front-line HCWs was 1.7% (2/167), and 4.6% (58/1265) in non-front-line HCWs (P = .04). In addition, non-front-line HCWs, non-medical staffs, history of contact with a confirmed COVID-19 case at home/family, unvaccinated status, fair compliance to personal protective equipment (PPE) standard, and initial presentation with pneumonia were significantly more common in HCWs with COVID-19 than those without COVID-19 (P < .05). Front-line HCWs, history of contact with a confirmed COVID-19 case at the clinical care areas in the hospital, vaccinated status, good compliance to PPE standards, and initial presentation with upper respiratory infection were significantly more common in HCWs without COVID-19 than those with COVID-19 (P < .05). Multivariate analysis revealed history of exposure with confirmed COVID-19 case at home or in family, unvaccinated status, non-frontline-HCWs, non-medical staffs, and fair compliance to PPE standard to be independent factors associated with COVID-19 in HCWs. COVID-19 was more common in non-front-line HCWs at this tertiary hospital. Thai guidelines on infection prevention and control for COVID-19 seem to be effective in preventing SARS-CoV-2 transmission. Therefore, the adherence to these recommendations should be encouraged.

Keywords: COVID-19, healthcare workers, prevalence, risk factors, SARS-CoV-2, Thailand


Link to Academic article: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508950/


Journal : Medicine (United States)2022, 101(38)


Bibliography     : Sirijatuphat, R., Leelarasamee, A., Horthongkham, N. (2022). Prevalence and factors associated with COVID-19 among healthcare workers at a university hospital in Thailand. Medicine (United States), 101(38), pp. E30837


 

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Process mining analysis to enhance systematic workflow of an IT company (2022)

Title              :  Process mining analysis to enhance systematic workflow of an IT company

Researcher       :  Porouhan, P. 
Department      : Graduate School of Information Technology, Siam University, Bangkok, Thailand

E-mail                 :

Link to article:  International Journal of Simulation and Process Modelling, 2022, 19(3-4), pp. 148–181. https://doi.org/10.1504/IJSPM.2022.131561

Publication: International Journal of Simulation and Process Modelling / in Scopus

Bibliography     : Porouhan, P. (2022). Process mining analysis to enhance systematic workflow of an IT company. International Journal of Simulation and Process Modelling, 19(3-4), 148–181. https://doi.org/10.1504/IJSPM.2022.131561


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Seroprevalence of Chikungunya and Zika virus in nonhuman primates: A systematic review and meta-analysis (2022)

Title           : Seroprevalence of Chikungunya and Zika virus in nonhuman primates: A systematic review and meta-analysis

Researcher       : Mongkol, N.Wang, F.S.Suthisawat, S., …Charoen, P.Boonnak, K.

Abstract            :  Chikungunya virus (CHIKV) and Zika virus (ZIKV) are mosquito-borne viruses that have caused several outbreaks worldwide. Aedes mosquitoes transmit these viruses mainly through sylvatic and urban transmission cycles. In the sylvatic cycle, nonhuman primates (NHPs) can be infected with CHIKV and ZIKV and may play an essential role as reservoirs for virus transmission. To improve our knowledge on the role of NHPs in the sylvatic cycle, we performed a systematic review and meta-analysis study on the seroprevalence of CHIKV and ZIKV worldwide in NHPs. According to the PRISMA guidelines, 17 CHIKV and 16 ZIKV seroprevalence studies in NHPs from 3 online databases: PubMed, Embase, and Scopus were selected. Data were extracted, including location and study year, type of NHP, sample size, serological tests, and seropositivity. All included studies have high-quality scores, between 5 and 8, corresponding to the grading criteria. Seroprevalence estimation was pooled using the ‘meta’ package in the R statistical software. The estimated pooled seroprevalence of CHIKV and ZIKV in NHP was 17% (95%CI: 5–34, I2: 99%, p < 0.05) and 6% (95% CI: 2–12, I2: 92%, p < 0.05), respectively. Most of the NHPs tested were wild Old World monkeys. The subgroup was analyzed by continents; high seropositive CHIKV and ZIKV were found in African NHPs at 35% (95% CI 9–66.0, I2 = 100) and 16% (95% CI 1–44, I2 = 97), respectively. While NHPs in America have 7% (95% CI 0-28, I2 = 99) and 2% (95% CI 1-3, I2 = 54) against CHIKV and ZIKV. In Asia, 6% (95% CI: 5–34, I2 = 96) CHIKV seroprevalence and 7% (95% CI 0–20, I2 = 98) ZIKV seroprevalence were found in NHP. This study provides a comprehensive overview of the seroprevalence of CHIKV and ZIKV among NHPs in various regions.

Keywords: Chikungunya virus, Zika virus, Seroprevalence, Nonhuman primates, Systematic review, Meta-analysis


Link to Academic article: https://doi.org/10.1016/j.onehlt.2022.100455


Journal : One Health2022, 15. 


Bibliography     : Mongkol, N.Wang, F.S.Suthisawat, S., Likhit, O., Charoen, P.Boonnak, K.  (2022). Seroprevalence of Chikungunya and Zika virus in nonhuman primates: A systematic review and meta-analysis. One Health, 15, 100455. https://doi.org/10.1016/j.onehlt.2022.100455


 

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Streptococcus pneumoniae Causing Invasive Diseases in Children and Adults in Central Thailand, 2012–2016 (2022)

Title           : Streptococcus pneumoniae Causing Invasive Diseases in Children and Adults in Central Thailand, 2012–2016

Researcher       : Wanatpreeya Phongsamart, Somporn Srifeungfung, Tanittha Chatsuwan, Pimpha Rungnobhakhun, Alan Maleesatharn and Kulkanya Chokephaibulkit

Link to articleVaccines, Volume 10, Issue 8, 21 August 2022, Pages 1-12. https://doi.org/10.3390/vaccines10081368


Journal : Vaccines  / in Scopus


Citation :  Phongsamart W., Srifeungfung S., Chatsuwan T., Rungnobhakhun P., Maleesatharn A. and Chokephaibulkit K. (2022). Streptococcus pneumoniae Causing Invasive Diseases in Children and Adults in Central Thailand, 2012–2016. Vaccines, 10(8), 1-12. https://doi.org/10.3390/vaccines10081368


ฐานข้อมูลงานวิจัย มหาวิทยาลัยสยาม   :  https://e-research.siam.edu/kb/streptococcus-pneumoniae-causing/

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Successful haploidentical hematopoietic stem cell transplantation with post-transplant cyclophosphamide in a child with X-linked chronic granulomatous disease: A first report in Asia (2022)

Title           :  Successful haploidentical hematopoietic stem cell transplantation with post-transplant cyclophosphamide in a child with X-linked chronic granulomatous disease: A first report in Asia

Researcher       : Chawisa Janjindamai Wiparat ManuyakornUsanarat AnurathapanSamart PakakasamaDuangrurdee WattanasirichaigoonWasu Kamchaisatian, Suwat BenjaponpitakSuradej Hongeng

Department     : Faculty of Medicine, Siam University, Bangkok, Thailand

E-mail                : med@siam.edu

Abstract            :  Background: HLA-matched hematopoietic stem cell transplantation (HSCT) is the curative treatment for chronic granulomatous disease (CGD).

Objective: To report a case of X-linked CGD with active infection successfully treated by haploidentical HSCT with post-transplant high dose cyclophosphamide (PTCY).

Methods: A 5-year-old Thai boy with CGD was undergone for haploidentical HSCT using PTCY with correction of the phagocytic function. He presented with Chromobacterium violaceum liver abscess at the age of 9 months and experienced recurrent perianal abscess and invasive pulmonary aspergillosis even receiving antimicrobial prophylaxis. PTCY was given on day 3 and 4, after CD34+ cells infusion.

Results: The peripheral blood-nucleated cell chimerism showed 100% on day 16 and remained 100%. Dihydrorhodamine (DHR) assay on day 108 and day 214 showed normal results. Currently at 22 months post HSCT, he does not receive antibiotic and anti-fungal prophylaxis.

Conclusions: Haploidentical HSCT with PTCY could be an effective treatment option for children with CGD.

Link to articleAsian Pacific Journal of Allergy and Immunology, 2022, 40(3), pp. 278–282. https://doi.org/10.12932/ap-290419-0551


Journal : Asian Pacific journal of allergy and immunology / in Scopus


Citation : Janjindamai, C., Manuyakorn, W., Anurathapan, U., Pakakasama S.,WattanasirichaigoonD., Kamchaisatian, W.,  Benjaponpitak, S. & Hongeng, S. (2022). Successful haploidentical hematopoietic stem cell transplantation with post-transplant cyclophosphamide in a child with X-linked chronic granulomatous disease: A first report in Asia. Asian Pac J Allergy Immunol, 40(3), 278–282. https://doi.org/10.12932/ap-290419-0551


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Synthesis of soluble calcium compound from skipjack tuna bones using edible weak acids (2022)

Title              :  Synthesis of soluble calcium compound from skipjack tuna bones using edible weak acids

Researcher       : Chakkapat Aenglong, Yu-Ming Wang, Maruj Limpawattana, Wanida Sukketsiri, Qing-Juan Tang, Wanwimol Klaypradit, Soraya Kerdpiboon

Department     : สำนักอธิการบดี มหาวิทยาลัยสยาม

E-mail                : maruj.lim@siam.edu

ฐานข้อมูลงานวิจัย มหาวิทยาลัยสยาม            :  –


Link to article: LWT, 2022, 162, 113460. https://doi.org/10.1016/j.lwt.2022.113460


Journal : LWT / in Scopus


Bibliography     :  Aenglong, C., Wang, Y. M., Limpawattana,  M., Sukketsiri, W., Tang, Q. J.,Klaypradit, W., & Kerdpiboon, S. (2022). Synthesis of soluble calcium compound from skipjack tuna bones using edible weak acids. LWT, 162, 113460. https://doi.org/10.1016/j.lwt.2022.113460


 

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Transforming learning for sufficiency economy philosophy and sustainable development through the triangle of living learning lab (2022)

Title              :  Transforming learning for sufficiency economy philosophy and sustainable development through the triangle of living learning lab

Researcher       Rukspollmuang, C.

Department     : Siam University, Bangkok, Thailand

Link to article: Asia Pacific Education Review, 2022, 23(4), pp. 595–610. https://doi.org/10.1007/s12564-022-09804-2


Journal : Asia Pacific Education Review / in Scopus


Bibliography     :  Rukspollmuang, C. (2022). Transforming learning for sufficiency economy philosophy and sustainable development through the triangle of living learning lab. Asia Pacific Education Review, 23(4), 595–610. https://doi.org/10.1007/s12564-022-09804-2


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Whole-genome single nucleotide variant phylogenetic analysis of Mycobacterium tuberculosis Lineage 1 in endemic regions of Asia and Africa (2022)

Title           : Whole-genome single nucleotide variant phylogenetic analysis of Mycobacterium tuberculosis Lineage 1 in endemic regions of Asia and Africa

Researcher       : Netikul, T.,[mfn]1[/mfn] Thawornwattana, Y.Mahasirimongkol, S., …Chongsuvivatwong, V.Palittapongarnpim, P.

Department     : 1Faculty of Medicine, Siam University, Bangkok, Thailand

E-mail                : med@siam.edu

Abstract            : Mycobacterium tuberculosis (Mtb) lineage 1 (L1) contributes considerably to the disease morbidity. While whole genome sequencing (WGS) is increasingly used for studying Mtb, our understanding of genetic diversity of L1 remains limited. Using phylogenetic analysis of WGS data from endemic range in Asia and Africa, we provide an improved genotyping scheme for L1. Mapping deletion patterns of the 68 direct variable repeats (DVRs) in the CRISPR region of the genome onto the phylogeny provided supporting evidence that the CRISPR region evolves primarily by deletion, and hinted at a possible Southeast Asian origin of L1. Both phylogeny and DVR patterns clarified some relationships between different spoligotypes, and highlighted the limited resolution of spoligotyping. We identified a diverse repertoire of drug resistance mutations. Altogether, this study demonstrates the usefulness of WGS data for understanding the genetic diversity of L1, with implications for public health surveillance and TB control. It also highlights the need for more WGS studies in high-burden but underexplored regions.


Link to Academic articlehttps://www.nature.com/articles/s41598-022-05524-0


Journal : Scientific Reports


Bibliography     : Netikul, T.Thawornwattana, Y.Mahasirimongkol, S., Yanai, H., WinMaung, H. M., Chongsuvivatwong, V.,… Palittapongarnpim, P. (2022). Whole-genome single nucleotide variant phylogenetic analysis of Mycobacterium tuberculosis Lineage 1 in endemic regions of Asia and Africa. Scientific Reports, 12(1), 1565.


 

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