Anatomical and Ultrasonography-Based Investigation to Localize the Arteries on the Central Forehead Region During the Glabellar Augmentation Procedure (2020)

Title           : Anatomical and Ultrasonography-Based Investigation to Localize the Arteries on the Central Forehead Region During the Glabellar Augmentation Procedure

Researcher       :  Phumyoo, T.Jiirasutat, N.Jitaree, B.RungsawangC., Uruwan, S.Tansatit, T.

Abstract            : Glabellar augmentation is one of the most popular cosmetic procedures but can entail severe complications caused by inadvertent intravascular injection of filler. Nevertheless, few studies have investigated the arteries on the glabellar and central forehead regions. The aim of this study was to correlate the topography and location of the arteries in this area with anatomical landmarks to propose a safety guideline. Two methods were used to investigate the glabellar and central forehead areas: dissection of 19 Thai embalmed cadavers, and ultrasonographic examination of 14 healthy Thai volunteers. At the level of the glabellar point, the horizontal distances from the midline to the arteries were 4.7 mm (central artery), 7.8 mm (paracentral artery), and 14.7 and 19.2 mm (superficial and deep branches of supratrochlear artery). The depths from the skin of the arteries were 3.1 mm (central artery), 4.8 mm (paracentral artery), and 4.2 and 5.9 mm (superficial and deep branches of supratrochlear artery). The periosteal artery was detected in 71.1% as a branch of either the superior orbitoglabellar or the supratrochlear artery. It ran in the supraperiosteal layer for a short course and penetrated the periosteum above the superciliary ridge or above the medial eyebrow, adhering tightly to the bony surface. This study suggests a safe injection technique for the glabella based on a thorough knowledge of arterial distribution and topography and color Doppler ultrasonographic examination prior to the injection, which is recommended to minimize the risk of severe complications. Clin. Anat. 33:370–382, 2020. © 2019 Wiley Periodicals, Inc.


Link to Academic article: https://doi.org/10.1002/ca.23516


Journal : Clinical Anatomy2020, 33(3).


Bibliography     : PhumyooT., JiirasutatN., JitareeB., RungsawangC., Uruwan, S., & Tansatit, T.(2020). Anatomical and Ultrasonography-Based Investigation to Localize the Arteries on the Central Forehead Region During the Glabellar Augmentation Procedure. Clinical Anatomy, 33(3), 370–382.


 

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Anti-aging potential and phytochemicals of Centella asiatica, Nelumbo nucifera, and Hibiscus sabdariffa extracts (2020)

Title           : Anti-aging potential and phytochemicals of Centella asiatica, Nelumbo nucifera, and Hibiscus sabdariffa extracts 

Researcher       Monsicha Khuanekkaphan1Chanai Noysang2Warachate Khobjai3

Department     : 1 Department of Health and Aesthetics, Thai Traditional Medicine College, Rajamangala University of Technology Thanyaburi, Pathum Thani, Thailand
2 Department of Innovation of Health Products, Thai Traditional Medicine College, Rajamangala University of Technology Thanyaburi, Pathum Thani, Thailand
3 Department of Applied Thai Traditional Medicine, Thai Traditional Medicine College, Rajamangala University of Technology Thanyaburi, Pathum Thani, Thailand

Abstract            :  Centella asiatica, Nelumbo nucifera Gaertn, and Hibiscus sabdariffa have been used as medicinal plants in Thailand. They are sources of phytochemicals that applications for esthetic and healthcare. The aim of this research was to examine the phytochemical constituents and anti-aging potential of these plants. The phytochemical compounds were performed using gas chromatography-mass spectrometry. The anti-aging activities were evaluated by 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2′-azinobis (3-ethylbenzothiazoline-6-sunfonic acid) (ABTS), anti-collagenase, and anti-elastase assays. The main interest phytochemical compounds of ethanolic extracts of C. asiatica, N. nucifera, H. sabdariffa were ethanol, 2-(-Octadecenyloxy), γ-sitosterol and hexadecanoic acid, and ethyl ester, respectively. The DPPH half-maximal inhibitory concentration (IC50) results of C. asiatica, N. nucifera, and H. sabdariffa were 0.32 ± 0.01, 0.34 ± 0.00, and 0.35 ± 0.01 mg/mL, respectively. The ABTS result of H. sabdariffa extract showed high inhibitory activity at IC50of the extract was 0.62 ± 0.12 mg/mL. The percentage of collagenase inhibition of C. asiatica, N. nucifera, and H. sabdariffa at 1.0 mg/mL was 78.13 ± 4.42, 85.94 ± 2.21, and 90.63 ± 0.00, respectively. The C. asiatica extract had a high percentage of elastase inhibition. Consequently, these research results suggest that phytochemicals may also provide a range of esthetic and health benefits. The phytochemical constituent could be used as anti-aging active ingredient for cosmetic and pharmaceutical industrials.

Keywords: Anti-aging, Centella asiatica, Hibiscus sabdariffa, Nelumbo nucifera, phytochemical


Link to Academic article: DOI: 10.4103/japtr.JAPTR_79_20


Journal : Journal of Advanced Pharmaceutical Technology and Researchthis link is disabled2020, 11(4).


Bibliography     :  Khuanekkaphan, M., Noysang, C., & Khobjai W. (2020). Anti-aging potential and phytochemicals of Centella asiatica, Nelumbo nucifera, and Hibiscus sabdariffa extracts. J Adv Pharm Technol Res, 11(4), 174-178. Retrieved from https://www.japtr.org/text.asp?2020/11/4/174/297699


 

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Association of HLA genotypes with phenytoin induced severe cutaneous adverse drug reactions in Thai children (2020)

Title           : Association of HLA genotypes with phenytoin induced severe cutaneous adverse drug reactions in Thai children

Researcher       : Clin.Prof.Suwat Benjaponpitak 

Department     : Faculty of Medicine, Siam University, Bangkok, Thailand

E-mail                : med@siam.edu

Abstract            :  Purpose: Phenytoin (PHT) is a common causative drug for severe cutaneous adverse drug reactions (SCARs) in children. SCARs, including drug reaction with eosinophilia and systemic symptoms (DRESS), Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), are associated with a variation in HLA genotypes. Blood screening for specific HLA allele before PHT prescription would help in the reduction of the incidence of PHT induced SCARs. This study was to investigate the association between variations of HLA genotypes and PHT induced SCARs in Thai children.

Methods: Cases were Thai children aged between 0-18 years diagnosed with SCARs from PHT. Control groups were Thai children of corresponding age who had taken PHT for a least 12 weeks without any hypersensitivity reaction and healthy population controls. Blood samples from both groups were collected for HLA genotyping using a reverse-sequence specific oligonucleotide (SSO) probes method. Carrier rates of HLA alleles were compared between 22 cases (17 DRESS and 5 SJS-TEN), 60 tolerant controls and 649 population controls.

Results: Two HLA alleles includingHLA-B*51:01 and HLA-C*14:02 were significantly associated with PHT induced DRESS (OR 5.83; 95 % CI 1.36-25.00, p = 0.022 and OR 5.85; 95 % CI 1.16-29.35, p = 0.039). HLA-B*38:02 was significantly associated with PHT induced SJS-TEN (OR12.67; 95 % CI 1.50-106.89, p = 0.044). Haplotype analysis demonstrated the association of HLA haplotype A*11:01-B*51:01-C*14:02 and PHT induced DRESS compared to tolerant controls and the healthy population control group (OR 8.92; 95 % CI 1.47-54.02, p = 0.019, and OR 10.2; 95 % CI 3.04-34.21, p = 0.002). HLA haplotype B*38:02-C*07:01 in PHT induced SJS-TEN was significantly higher than those in tolerant controls and the healthy population control group (40 % vs 3.3 % vs 0.3 %; OR 19.33; 95 % CI 1.98-188.59, p = 0.027 and OR 215.67; 95 % CI 22.40-2076.04, p = 0.0003. HLA-B*15:02 was not associated with PHT induced SCARs.

Significance: An association betweenHLA-B*51:01 and HLA-C*14:02 and PHT induced DRESS and HLA-B*38:02 and PHT induced SJS-TEN has been demonstrated in Thai children.

Keywords: Drug reaction; HLA-B*38:02; HLA-B*51:01; HLA-C*14:02; Phenytoin.

Link to article : Epilepsy Research, 2020, 162, 106321. DOI: 10.1016/j.eplepsyres.2020.106321


Journal :  Epilepsy Research    Volume 162, May 2020,


Bibliography     :  Manuyakorn, W., Likkasittipan, P., Wattanapokayakit, S., Suvichapanich, S., Inunchot, W., Wichukchinda, N., Khongkhatithuml, C., Thampratankul, L., Kamchaisatian, W., Benjaponpitak, S., & Mahasirimongkol, S. (2020, May). Association of HLA genotypes with phenytoin induced severe cutaneous adverse drug reactions in Thai children. Epilepsy Res, 162, 106321. doi: 10.1016/j.eplepsyres.2020.106321. Epub 2020 Mar 13. PMID: 32272329.

 


 

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Cesarean section rate based on the robson 10-group classification at Rajavithi Hospital from 2015-2018 (2021)

Title           : Cesarean section rate based on the robson 10-group classification at Rajavithi Hospital from 2015-2018

Researcher       : Khornwong, S., Kovavisarach, E.

Abstract            : Objectives: To analyze cesarean section (CS) rates based on the Robson 10-group classification system (TGCS) and to examine the trends of cesarean section rates at Rajavithi Hospital (RH) between 2015 and 2018.

Materials and Methods: This cross-sectional study included all deliveries in RH between 1st January, 2015 and 31st December, 2018. The TGCS was used to categorize cesarean deliveries and all data collected.

Results: A total of 19,840 deliveries were analyzed. The annual CS rates were 35.5% (1710/4813), 36.6% (1809/4949), 35.2% (1836/5223) and 34.8% (1689/4855) in 2015, 2016, 2017 and 2018, respectively. The trend of the CS rates in each group and that of relative and absolute contributions were similar within the study period (p = 0.290). Group 1, 3 and 10 accounted for almost 70% of the study population and multiparous women with previous CS in (30.8%, 32.6%, 31.9% and 31.9%; p = 0.718), followed by group 2 (17.5%, 18%, 18.9% and 17.9%; p = 0.506) and group 1 (16.1%, 16.8%, 14.4% and 15.2%; p = 0.211), respectively.

Conclusion: The overall CS rate during the four-year period 2015-2018 varied between 34.8% and 36.6%, and the highest relative and absolute contribution to the overall CS rate at.

Keywords: Cesarean section rate The Robson 10-group classification Rajavithi Hospital


Link to Academic article: DOI: https://doi.org/10.14456/tjog.2021.23


Journal : Thai Journal of Obstetrics and Gynaecology2021, 29(4).


Bibliography     : Khornwong, S.Kovavisarach, E., (2021). Cesarean section rate based on the robson 10-group classification at Rajavithi Hospital from 2015-2018. Thai Journal of Obstetrics and Gynaecology, 29(4), 191–197.


 

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Changing the Landscape: An Introduction to the Agricultural and Food Chemistry Technical Program at the 258th American Chemical Society National Meeting in San Diego(2020)

 

Title              :  Changing the Landscape: An Introduction to the Agricultural and Food Chemistry Technical Program at the 258th American Chemical Society National Meeting in San Diego

Researcher       Michael Appell, Atanu Biswas, SeChin Chang, Wei Chen, H. N. Cheng, Jim Daily III, Xuetong Fan, Michael Granvogl, Mingming Guo, Yoshihiro Ito, Tony Jin, Masuko Kobori, Jane V. Leland, LinShu Liu, Yangchao Luo, Shaun MacMahon, Kanjana Mahattanatawee*, Sunghyun Nam, Coralia Osorio, Bosoon Park, Daxi Ren, Shengmin Sang, Fereidoon Shahidi, Michael Tunick, Chibuike C. Udenigwe, Qin Wang, Wallace H. Yokoyama, Liangli Lucy Yu, Yaqiong Zhang, and Yingdong Zhu

Department     : *Food Technology Department, Faculty of Science, Siam University

E-mail                : *kanjana@siam.edu

ฐานข้อมูลงานวิจัย มหาวิทยาลัยสยาม            :  –

Link to article:  Journal of Agricultural and Food Chemistry, 2020, 68(46), pp. 12769–12772. https://doi.org/10.1021/acs.jafc.0c02809

Publication: Journal of Agricultural and Food Chemistry  / in Scopus

Bibliography     : Appell, M.Biswas, A.Chang, S., Chen, W.,Cheng, H. N., Daily III, J., Fan, X., Granvogl, M., Guo, M.,  Ito, Y.,Jin, T., Kobori, M.,  Leland, J. V.,  Liu, L., Luo, Y.,MacMahon, S., Mahattanatawee, K.,Nam, S., Osorio,C., …Zhu, Y. (2020). Journal of Agricultural and Food Chemistry, 68(46), 12769–12772. https://doi.org/10.1021/acs.jafc.0c02809


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Chemical evaluation and antibacterial activity of novel bioactive compounds from endophytic fungi in Nelumbo nucifera (2020)

Title           : Chemical evaluation and antibacterial activity of novel bioactive compounds from endophytic fungi in Nelumbo nucifera

Researcher       : Techaoei, S.Jirayuthcharoenkul, C.Jarmkom, K.Dumrongphuttidecha, T.Khobjai, W.

Department     :

Abstract            :  The objective of this study was to characterize an endophytic fungi producing-bioactive compound from the aquatic plant, Nelumbo nucifera. All parts of such plant were cleaned with surface sterilization technique and cultured on potato dextrose agar to isolate endophytic fungi. The identification was characterized by morphological and molecular technique. Fungal isolates were screened to discover antimicrobial activities by disc diffusion method against Methicillin-resistant Staphylococcus aureus DMST20651 (MRSA). MIC and MBC for those crude fungal extracts were determined. Finally, the chemical profile of crude extract was determined by gas chromatography and mass spectrometry. Six endophytic fungi were isolated from the surface-satirized parts of N. nucifera. Based on disc diffusion assay, the highest antibacterial activity against MRSA was isolate ST9.1 identified as Aspergillus cejpii. Results demonstrated that the ethyl acetate extraction had more active fractions with MIC of 2.5 mg/ml and MBC concentration of 50.0 mg/ml. The crude extracts were developed to identify the chemical constituents by gas chromatography and mass spectrometry. The major component of crude extract of endophytic fungi was 5-(1H-Indol-3-yl)-4,5-dihydro-[1,2,4]triazin-3-ylamine (C11H11N5). Thus, the plant could be used in the treatment of infectious diseases caused by bacterial pathogen.

Keywords: Antimicrobial activity, N. nucifera, Methicillin-resistant S. aureus, Endophytic fungi


Link to Academic article: https://doi.org/10.1016/j.sjbs.2020.08.037


Journal : Saudi Journal of Biological Sciencesthis2020, 27(11)


Bibliography     : Techaoei, S.Jirayuthcharoenkul, C.Jarmkom, K.Dumrongphuttidecha, T., & Khobjai, W. (2020). Chemical evaluation and antibacterial activity of novel bioactive compounds from endophytic fungi in Nelumbo nucifera. Saudi Journal of Biological Sciencesthis, 27(11), 2883–2889. Retrieved from https://doi.org/10.1016/j.sjbs.2020.08.037


 

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Comparative in vitro activity of sitafloxacin against multidrug-resistant and carbapenem-resistant acinetobacter baumannii clinical isolates in Thailand (2020)

Title           : Comparative in vitro activity of sitafloxacin against multidrug-resistant and carbapenem-resistant acinetobacter baumannii clinical isolates in Thailand

Researcher       : Taniya Paiboonvong1,Vipavee Rodjun2,Jantana Houngsaitong1,Mullika Chomnawang3,Preecha Montakantikul2,Suvatna Chulavatnatol2*

1 Department of Pharmacy, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand
2 Faculty of Pharmacy, Siam University, Bangkok, Thailand
3 Department of Microbiology, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand

ฐานข้อมูลงานวิจัย มหาวิทยาลัยสยาม            :  –


Link to article: Pharmaceutical Sciences Asia, 2020, 47(1), pp. 37–42 https://pharmacy.mahidol.ac.th/journal/journalabstractDetail.php?jvol=47&jpart=1&jconnum=4


Journal :Pharmaceutical Sciences Asia/ Scopus


Citation : Paiboonvong, T., Rodjun, V., Houngsaitong, J., Chomnawang, M., Montakantikul,P., & Chulavatnatol, S. (2020). Comparative in vitro activity of sitafloxacin against multidrug-resistant and carbapenem-resistant acinetobacter baumannii clinical isolates in Thailand. Pharmaceutical Sciences Asia, 47(1), 37–42. https://doi.org/10.29090/psa.2020.01.019.0012

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Compound Heterozygous PGM3 Mutations in a Thai Patient with a Specific Antibody Deficiency Requiring Monthly IVIG Infusions (2020)

Title           :  Compound Heterozygous PGM3 Mutations in a Thai Patient with a Specific Antibody Deficiency Requiring Monthly IVIG Infusions

Researcher       : Clin.Prof.Suwat Benjaponpitak 

Department     : Faculty of Medicine, Siam University, Bangkok, Thailand

E-mail                : med@siam.edu

Link to Academic articleDOI: 10.1007/s10875-019-00693-6


Journal :  Journal of Clinical Immunology  Vol. 40, No. 1, 2020


Bibliography     : Ittiwut, C., Manuyakorn, W., Tongkobpetch, S., Benjaponpitak, S., Fisher, M. R., Milner, J. D., Lyons, J. J., Suphapeetiporn, K., & Shotelersuk, V. (2020, January). Compound Heterozygous PGM3 Mutations in a Thai Patient with a Specific Antibody Deficiency Requiring Monthly IVIG Infusions. J Clin Immunol, 40(1), 227-231. doi: 10.1007/s10875-019-00693-6. Epub 2019 Nov 9. PMID: 31707513.


 

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Conventional and microwave-assisted extraction for bioactive compounds from dried coffee cherry peel by-products and antioxidant activity of the aqueous extracts (2020)

Title              :  Conventional and microwave-assisted extraction for bioactive compounds from dried coffee cherry peel by-products and antioxidant activity of the aqueous extracts

Researcher       : Thaiphanit, S.Wedprasert, W.Srabua, A.

Department     : ภาควิชาเทคโนโลยีการอาหาร คณะวิทยาศาสตร์ มหาวิทยาลัยสยาม

E-mail                : somruedee.tha@siam.edu

ฐานข้อมูลงานวิจัย มหาวิทยาลัยสยาม: https://e-research.siam.edu/kb/conventional-and-microwave-assisted-extraction-for-bioactive-compounds-from-dried-coffee-cherry-peel-by-products-and-antioxidant-activity-of-the-aqueous-extracts/


Link to article: ScienceAsia, 2020, 46 S(1), pp. 12–18. https://www.scienceasia.org/content/viewabstract_progress.php?ms=11118


Journal :  ScienceAsia / in Scopus


Bibliography     :  Somruedee Thaiphanit, Warintorn Wedprasert and Aristha Srabua. (2020). Conventional and microwave-assisted extraction for bioactive compounds from dried coffee cherry peel by-products and antioxidant activity of the aqueous extracts. ScienceAsia, 46S(1), 12-18.


 

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Effect of actinomycin D isolated from the cultured broth of marine streptomyces spp. On cell division protein FtsZ (2020)

Title           :  Effect of actinomycin D isolated from the cultured broth of marine streptomyces spp. On cell division protein FtsZ

Researcher       :  Phennapa Charoenwiwattanakij, Jaturong Pratuangdejkul, Sumet chongruchiroj, Khanit Suwanborirux, Chitti Thawai, Jiraporn Chingunpitak and Veena Satitpatipan

Link to article  Chiang Mai Journal of Science, 2020, 47(3), pp. 362–377. https://epg.science.cmu.ac.th/ejournal/journal-detail.php?id=10910


Journal : Chiang Mai Journal of Science  / in Scopus


Citation : Charoenwiwattanakij, P., Pratuangdejkul, J., Chongruchiroj, S., Suwanborirux, K., Thawai, C., Chingunpitak, J.,  & Satitpatipan, V., (2020). Effect of actinomycin D isolated from the cultured broth of marine streptomyces spp. On cell division protein FtsZ. Chiang Mai Journal of Science, 47(3), 362–377.


ฐานข้อมูลงานวิจัย มหาวิทยาลัยสยาม  : 

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