2405. In vitro Synergistic Activity of Sitafloxacin in Combination With Colistin Against Clinical Isolates of Multidrug-Resistant Acinetobacter baumannii in Thailand (2018)Copy)
Title : 2405. In vitro Synergistic Activity of Sitafloxacin in Combination With Colistin Against Clinical Isolates of Multidrug-Resistant Acinetobacter baumannii in Thailand
Researcher : Vipavee Rodjun2,Taniya Paiboonvong1,Jantana Houngsaitong1,Preecha Montakantikul2,
1 Department of Pharmacy, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand
2 Faculty of Pharmacy, Siam University, Bangkok, Thailand
ฐานข้อมูลงานวิจัย มหาวิทยาลัยสยาม : –
Link to article: Open Forum Infectious Diseases, Volume 5, Issue suppl_1, November 2018, Pages S718–S719, https://doi.org/10.1093/ofid/ofy210.2058
Journal : Open Forum Infectious Diseases / Scopus
Citation : Rodjun, V., Paiboonvong, T., Houngsaitong, J., & Montakantikul,P. (2018). 2405. In vitro Synergistic Activity of Sitafloxacin in Combination With Colistin Against Clinical Isolates of Multidrug-Resistant Acinetobacter baumannii in Thailand. Open Forum Infectious Diseases, 5(Suppl 1), S718–S719. https://doi.org/10.1093/ofid/ofy210.2058
A Cadaveric Study of Dye Spreading: Determining the Ideal Injection Pattern for Masseter Hypertrophy (2021)
Title : A Cadaveric Study of Dye Spreading: Determining the Ideal Injection Pattern for Masseter Hypertrophy
Researcher : Sermswan, P., Tansatit, T., Meevassana, J., Panchaprateep, R.
Abstract : BACKGROUND: Masseter hypertrophy is the main cause of an asymmetrical and squared lower facial contour in the Asian community. Botulinum toxin injection technique is crucial to treat this condition.
OBJECTIVE: To improve injection techniques for masseter hypertrophy by elucidating the distribution of the injections within the masseter.
METHODS: Thirty masseter muscles were divided into 6 groups of 5 muscles each. Each group received one 0.2- or 0.3-mL injection at Point A, B, or C according to a three-point technique. Muscle dimensions and dye of the primary and secondary dye spreading were measured.
RESULTS: The average muscle length, width, and thickness were 69.87, 33.50, and 11.23 mm, respectively. The average primary longitudinal and horizontal spreading was 36.56 and 15.60 mm, respectively. No statistically significant difference was found between 0.2- and 0.3-mL injections at each point.
CONCLUSION: The three-point technique best fits in the safe zone and should be the standard injection technique for masseter hypertrophy. Injection at Points B and C may create secondary spreading that affect the risorius muscle and the parotid gland which are the cause of asymmetrical smiling and xerostomia, respectively. The dosage should be adjusted according to the muscle volume and not only the thickness.
Link to Academic article: DOI: 10.1097/DSS.0000000000003171
Journal : ,
Bibliography : Sermswan, P., Tansatit, T., Meevassana, J., & Panchaprateep, R. (2021). A Cadaveric Study of Dye Spreading: Determining the Ideal Injection Pattern for Masseter Hypertrophy.
A Dimensional Consistency Aware Time Domain Analysis of the Generic Fractional Order Biquadratic System (2022)
Title : A Dimensional Consistency Aware Time Domain Analysis of the Generic Fractional Order Biquadratic System
Researcher : Banchuin, R. and Roungsan Chaisricharoen
Department : Faculty of Engineering & Graduated School of IT, Siam University, Bangkok, Thailand
Email : rawid.ban@siam.edu
Abstract : In this research, the time domain analysis of the fractional order biquadratic system with nonzero input and nonzero damping ratio has been performed. Unlike the previous works, the analysis has been generically done with dimensional consistency awareness without referring to any specific physical system where nonzero input and nonzero damping ratio have been allowed. The fractional differential equation of the system has been derived and analytically solved. The physical measurability of the dimensions of the fractional derivative terms which have been defined in Caputo sense, and response with significantly different dynamic from its dimensional consistency ignored counterpart have been obtained due to our dimensional consistency awareness. The resulting solution is applicable to the fractional biquadratic systems of any kind with any physical nature. Based on such solution and numerical simulations, the influence of the fractional order parameter to all major time domain parameters have been studied in detailed. The obtain results provide insight to the fractional order biquadratic system with dimensional consistency awareness in a generic point of view.
Keywords: fractional order biquadratic system, fractional differential equation, fractional time component parameter, dimensional consistency, time domain analysis
Link to article : Journal of Mobile Multimedia, 2022, Vol. 18 No.3, pp. 789–806. https://doi.org/10.13052/jmm1550-4646.18316
Journal : Journal of Mobile Multimedia / in Scopus
Citation : Banchuin, R., & Chaisricharoen R. (2022). A dimensional consistency aware time domain analysis of the generic fractional order biquadratic system. Journal of Mobile Multimedia, 18(3), 789–806. https://doi.org/10.13052/jmm1550-4646.18316
ฐานข้อมูลงานวิจัย มหาวิทยาลัยสยาม : https://e-research.siam.edu/kb/a-dimensional-consistency/
A novel generalized fractional-order memristor model with fully explicit memory description (2023)
Title : A novel generalized fractional-order memristor model with fully explicit memory description
Researcher : Banchuin, R.
Department : Faculty of Engineering, Siam University, Bangkok, Thailand
Email : rawid.ban@siam.edu
Abstract : In this work, a novel generalized mathematical model of fractional-order memristor with fully explicit memory description has been proposed. For obtaining such full explicit memory description, the Atangana-Baleanu fractional derivative in Liouville-Caputo sense, which employs a nonsingular kernel, has been adopted as the mathematical basis. The proposed model has been derived without regarding to any specific conventional memristor. A comparison with the singular kernel fractional derivative-based model has been made. The behavioral analysis of the fractional-order memristor based on the proposed model has been performed, where both DC and AC stimuli have been considered. In addition, its application to the practical fractional-order memristor-based circuit and its extension to the fractional-order memreactance have also been shown. Unlike the singular kernel fractional derivative-based model, a fully explicit memory description can be obtained by ours. Many other interesting results that are contradict to the previous singular kernel fractional derivative-based ones, e.g., the fractional-order memristor that can be locally active, have been demonstrated. The abovementioned extension can be conveniently performed. In summary, this is the first time that a nonsingular kernel fractional derivative has been applied to the fractional-order memristor modeling and the resulting model with a fully explicit memory description has been proposed. The proposed model is also highly generic, applicable to the practical circuit, and extendable to the fractional-order memreactance.
Link to article : International Journal of Circuit Theory and Applications, 2023, 51(4), pp. 1935–1957. https://doi.org/10.1002/cta.3410
Journal : International Journal of Circuit Theory and Applications / in Scopus
Bibliography : Banchuin, R. (2023). A novel generalized fractional-order memristor model with fully explicit memory description. International Journal of Circuit Theory and Applications, 51(4), 1935–1957. https://doi.org/10.1002/cta.3410
A Pilot Study of 0.4% Povidone-Iodine Nasal Spray to Eradicate SARS-CoV-2 in the Nasopharynx (2022)
Title : A Pilot Study of 0.4% Povidone-Iodine Nasal Spray to Eradicate SARS-CoV-2 in the Nasopharynx
Researcher : Sirijatuphat, R.,1 Leelarasamee, A.,1,2 Puangpet, T.,3 Thitithanyanont, A.4
Department : 1Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand; 2Faculty of Medicine, Siam University, Bangkok, Thailand; 3Samut Sakhon Hospital, Samut Sakhon, Thailand; 4Department of Microbiology, Faculty of Science, Mahidol University, Bangkok, Thailand
Abstract : Purpose: This study aimed to evaluate the virucidal efficacy of 0.4% povidone-iodine (PVP-I) nasal spray against SARS-CoV-2 in the patients’ nasopharynx at 3 minutes and 4 hours after PVP-I exposure.
Patients and Methods: The study was an open-label, before and after design, single-arm pilot study of adult patients with RT-PCR-confirmed COVID-19 within 24 hours. All patients received three puffs of 0.4% PVP-I nasal spray in each nostril. Nasopharyngeal (NP) swabs were collected before the PVP-I spray (baseline, left NP samples), and at 3 minutes (left and right NP samples) and 4 hours post-PVP-I spray (right NP samples). All swabs were coded to blind assessors and transported to diagnostic laboratory and tested by RT-PCR and cultured to measure the viable SARS-CoV-2 within 24 hours after collection.
Results: Fourteen patients were enrolled but viable SARS-CoV-2 was cultured from 12 patients (85.7%). The median viral titer at baseline was 3.5 log TCID50/mL (IQR 2.8– 4.0 log TCID50/mL). At 3 minutes post-PVP-I spray via the left nostril, viral titers were reduced in 8 patients (66.7%). At 3 minutes post-PVP-I, the median viral titer was 3.4 log TCID50/mL (IQR 1.8– 4.4 log TCID50/mL) (P=0.162). At 4 hours post-PVP-I spray via the right nostril, 6 of 11 patients (54.5%) had either the same or minimal change in viral titers. The median viral titer 3 minutes post-PVP-I spray was 2.7 log TCID50/mL (IQR 2.0– 3.9 log TCID50/mL). Four hours post-PVP-I spray the median titer was 2.8 log TCID50/mL (IQR 2.2– 3.9 log TCID50/mL) (P=0.704). No adverse effects of 0.4% PVP-I nasal spray were detected.
Conclusion: The 0.4% PVP-I nasal spray demonstrated minimal virucidal efficacy at 3 minutes post-exposure. At 4 hours post-exposure, the viral titer was considerably unchanged from baseline in 10 cases. The 0.4% PVP-I nasal spray showed poor virucidal activity and is unlikely to reduce transmission of SARS-CoV-2 in prophylaxis use.
Keywords: povidone iodine, COVID-19, SARS-CoV-2, viral eradication, viral culture, nasopharyngeal swab
Link to Academic article: DOI https://doi.org/10.2147/IDR.S391630
Journal : ,
Bibliography : Sirijatuphat, R., Leelarasamee, A., Puangpet, T., & Thitithanyanont, A. (2022). A Pilot Study of 0.4% Povidone-Iodine Nasal Spray to Eradicate SARS-CoV-2 in the Nasopharynx. ,
A randomized, controlled trial of prulifloxacin as conversion therapy after intravenous carbapenem in the treatment of acute pyelonephritis caused by third generation cephalosporin resistant pathogens: A pilot study (2023)
Title : A randomized, controlled trial of prulifloxacin as conversion therapy after intravenous carbapenem in the treatment of acute pyelonephritis caused by third generation cephalosporin resistant pathogens: A pilot study
Researcher : Apichot So-Ngern,Supunnee Jirajariyavej, Huttaya Thuncharoon, Nuttha Khunthupat, Teerachai Chantarojanasiri and Preecha Montakantikul
Link to article: Clinical and Translational Science, Volume 16, Issue 12, December 2023, Pages 2709-2718. https://doi.org/10.1111/cts.13665
Journal : Clinical and Translational Science / in Scopus
Citation : So-Ngern A, Jirajariyavej S, Thuncharoon H, Khunthupat N, Chantarojanasiri T and Montakantikul P. (2023). A randomized, controlled trial of prulifloxacin as conversion therapy after intravenous carbapenem in the treatment of acute pyelonephritis caused by third generation cephalosporin resistant pathogens: A pilot study. Clinical and Translational Science, 16(12), 2709-2718. https://doi.org/10.1111/cts.13665
ฐานข้อมูลงานวิจัย มหาวิทยาลัยสยาม : https://e-research.siam.edu/kb/a-randomized-controlled-trial-of-prulifloxacin/
Achieving the Most Effective Hanging Points at the Lower End of the Face for Thread Lifting: Quantitative Measurement of Tissue Resistance in Different Facial Layers (2021)
Title : Achieving the Most Effective Hanging Points at the Lower End of the Face for Thread Lifting: Quantitative Measurement of Tissue Resistance in Different Facial Layers
Researcher : Rungsawang, C., Tansatit, T., Fasunloye, L.K., Uruwan, S.
Abstract : The thread lift procedure is a minimally invasive alternative to facelift surgery. The hanging point, which the terminal end of the thread is hooked into, is an important component. If it is loose and cannot stabilize the passage when the inserted thread is pulled, the lifting effect will fail. Therefore, the aim of this study was to elucidate the ability of the tissue to support the thread attachment in the different facial layers while performing this procedure. Twenty hemi-faces of 10 soft cadavers, which were divided into 45 blocks, were used to measure the tissue resistance in the midface area. The resistance of the soft tissue in the four facial layers in each block was measured while a 22G cannula connected with a force gauge was passed through it. The results showed that the tissue resistance in the sub-SMAS was higher than the SMAS and subcutaneous layers in the blocks located in the nasolabial and perioral regions. This was also significantly greater than the resistance in the subcutaneous layer in the three medial blocks below the oral commissure (P < 0.05). However, the low resistance of the sub-SMAS was found in the blocks located in the buccal and lower parotidomasseteric regions. Thus, it was preferable that the hanging point was based in the deep plane (sub-SMAS and SMAS layers) of the nasolabial, perioral, and upper parotidomasseteric regions. Moreover, the sub-SMAS layer within the buccal and lower parotidomasseteric regions should be avoided due to the loose attachment in the buccal capsule and subplatysmal fat.
Link to Academic article: DOI: 10.1097/GOX.0000000000003701
Journal : ,
Bibliography : Rungsawang, C., Tansatit, T., Fasunloye, L. K., & Uruwan, S. (2021). Achieving the Most Effective Hanging Points at the Lower End of the Face for Thread Lifting: Quantitative Measurement of Tissue Resistance in Different Facial Layers. , 9(7)
Advances in Natural Product Extraction Techniques, Electrospun Fiber Fabrication, and the Integration of Experimental Design: A Comprehensive Review (2023) (Copy)
Title : Advances in Natural Product Extraction Techniques, Electrospun Fiber Fabrication, and the Integration of Experimental Design: A Comprehensive Review
Researcher : Juthaporn Ponphaiboon, Wantanwa Krongrawa, Wah Wah Aung, Nawinda Chinatangkul,Sontaya Limmatvapirat and Chutima Limmatvapirat
Link to article : Molecules, Volume 28, Issue 13, 5163. https://doi.org/10.3390/molecules28135163
Citation : Ponphaiboon J., Krongrawa W., Aung W.W., Chinatangkul N., Limmatvapirat S., & Limmatvapirat C. (2023). Advances in natural product extraction techniques, electrospun fiber fabrication, and the integration of experimental design: A comprehensive review. Molecules,28(13), 5163. https://doi.org/10.3390/molecules28135163
Journal : Molecules / in Scopus
ฐานข้อมูลงานวิจัย มหาวิทยาลัยสยาม : https://e-research.siam.edu/kb/advances-in-natural-product/
Aldosterone nongenomically induces angiotensin II receptor dimerization in rat kidney: Role of mineralocorticoid receptor and NADPH oxidase (2019)
Title : Aldosterone nongenomically induces angiotensin II receptor dimerization in rat kidney: Role of mineralocorticoid receptor and NADPH oxidase
Researcher : Sinphitukkul, K., Manotham, K., Eiam-Ong, S., Eiam-Ong, S.
Abstract :
Introduction: Previous in vitro studies demonstrated that aldosterone nongenomically induces transglutaminase (TG) and reactive oxygen species (ROS), which enhanced angiotensin II receptor (ATR) dimerization. There are no in vivo data in the kidney.
Material and methods: Male Wistar rats were intraperitoneally injected with normal saline solution, or aldosterone (Aldo: 150 μg/kg BW); or received pretreatment with eplerenone (mineralocorticoid receptor (MR) blocker, Ep. + Aldo), or with apocynin (nicotinamide adenine dinucleotide phosphate (NADPH) oxidase inhibitor, Apo. + Aldo) 30 min before aldosterone. Thirty minutes after aldosterone injection, protein abundances of dimeric and monomeric forms of AT1R and AT2R, and protein abundances and localizations of TG2 and p47phox, a cytosolic subunit of NADPH oxidase, were determined by Western blot analysis and immunohistochemistry, respectively.
Results: Protein abundances of dimeric forms of AT1R and AT2R were enhanced by 170% and 70%, respectively. Apocynin could block dimeric forms of both receptors while eplerenone inhibited only AT2R. Monomeric protein levels of both receptors were maintained. Aldosterone significantly enhanced TG2 and p47phox protein abundances, which were blunted by eplerenone or apocynin. Aldosterone stimulated p47phox protein expression in both the cortex and the medulla while TG2 was induced mostly in the medulla. Eplerenone or apocynin normalized the immunoreactivity of both TG2 and p47phox.
Conclusions: This is the first in vivo study demonstrating that aldosterone nongenomically increases renal TG2 and p47phox protein expression and then activates AT1R and AT2R dimerizations. Aldosterone-stimulated AT1R and AT2R dimerizations are mediated through activation of NADPH oxidase. Aldosterone-induced AT1R dimer formation is an MR-independent pathway, whereas the formation of AT2R dimer is modulated in an MR-dependent manner.
Keywords: NADPH oxidase; aldosterone; angiotensin II receptor dimerization; mineralocorticoid receptor; nongenomic action; rat kidney.
Link to Academic article: DOI: 10.5114/aoms.2019.87135
Journal : ,
Bibliography : Sinphitukkul, K., Manotham, K., Eiam-Ong, S., & Eiam-Ong, S. (2018). Aldosterone nongenomically induces angiotensin II receptor dimerization in rat kidney: role of mineralocorticoid receptor and NADPH oxidase.
An Analysis of the Relationship of Social Application Usage on Academic Achievement of Nursing Students, Siam University (2016)
Title : An Analysis of the Relationship of Social Application Usage on Academic Achievement of Nursing Students, Siam University
Researcher : Assist. Prof. Dr. Jaratdao Reynolds, Assist. Prof. Dr. Orntipa Songsiri and Assist. Prof. Dr. Somrudee Chenkitiyanon
Department : Faculty of Nursing, Siam University, Bangkok, Thailand
E-mail : jaratdao@gmail.com
Abstract : As we enter the 21st century, social application/networking is being used by an increasing portion of world’s population, especially adolescents and young adult on a day- to-day regular activities. Students are increasingly uses these social application /networks for both academic and non-academic reasons. However, the use of this social application has led to debate over whether or not it has impacted on students’ life as well as their academic achievement. Some studies identified that social application/networking may be the tool used in helping to develop and enhance students’ skill required for 21st century (Tuan and tu,2013). Therefore, this study was aimed to explore the relationship of social application usage among nursing students on their academic performance (GPAs). It took into account on how students participated on socialn application, time invested by students on social application, frequency of usage and the purposes of usage. The study was a cross-sectional survey, using the developed questionnaire. The data was collected from 272 students in the second and fourth year of nursing program, Siam University during the academic year 2014-2015. The data were statistically analyzed by calculating percentage, mean, standard deviation, and Pearson correlation analysis. Results indicated that all of the nursing students were using at least one form of social application. For the use of social applications, it was obviously that, Facebook and Line were the most popular social application students used (100%), followed by google (89.7%) and instragram (57.57%).Results of frequency of usage indicated that 98.16 percent of students visited a social application/networking several times a day. In term of the purposed for using the social applications, they were varied. Even though students generally use social application for academic purposes; they also use it for nonacademic matters .For non academic purposed, the results shown that 94.12 percent of students reported used the social applications for communication with friends and family, and 72.80 percent reported they used for entertainment when they felt bored. Additional reasons reported included companionship (47.06%), and making friends (27.21%). For academic purposed, searching for information was the most reason students used (77.95%), followed by learning and sharing resources (66.91%), exchange ideas and discussion (48.16%) and professional networking (36.03%) respectively. The finding of this study found negative correlations between time spent on social application usage with students’ GPAs. In other words, GPAs decreased as the amount of time spent on social application usage. The purposes of usage was also shown to be significantly correlated with students’ GPAs. The students who use social application for academic purposes seem to earned better GPAs.Therefore, in the light of globalization and the information age, integration of these social application in students’ life is unavoidable,however findingmiddle ground has become a challenge.
Proceeding : การประชุมวิชาการระดับชาติ สมาคมสถาบันอุดมศึกษาเอกชนแห่งประเทศไทย ประจำปี 2559 วันที่ 26 พฤษภาคม 2559 มหาวิทยาลัยภาคตะวันออกเฉียงเหนือ APHEIT Conference 2016
Link to Proceeding: http://apheitconference.siam.edu/index.php/en/proceedings-2012-2016
Bibliography : Jaratdao Reynolds, Orntipa Songsiri & Somrudee Chenkitiyanon. (2016). An analysis of the relationship of social application usage on academic achievement of nursing students, Siam University. In Proceedings of Conference 2016 (pp. 170-171). Khon Kaen: North Eastern University.