Phytonutrient screening by gas chromatography–mass spectrometry and anti-aging properties of glycosmis pentaphylla (Retz.) dc. (som-chuen) extracts (2021)

Title           : Phytonutrient screening by gas chromatography–mass spectrometry and anti-aging properties of glycosmis pentaphylla (Retz.) dc. (som-chuen) extracts

Researcher       : Dumrongphuttidecha, T., Khobjai, W., Techaeoi, S., Jarmkom, K., Thungmungmee, S.

Department     :

Abstract            :  Objective: The aims of this study were to screen the phytonutrient constituents and investigate their anti-aging property of leaves and bark of
Glycosmis pentaphylla (Retz.) DC. (GP).
Methods: GP is the medicinal plant which used as traditional medicine. Glycosmis pentaphylla leaves (GPL) and Glycosmis pentaphylla bark (GPB) of
GP were extracted with ethanol. The gas chromatography–mass spectrometry was used for phytonutrients analysis. The anti-aging properties were
performed using ABTS assay, deoxyribose degradation assay, bovine serum albumin (BSA)-fructose model, and matrix metalloproteinase 1 (MMP-1)
inhibitory activity.
Results: The important phytonutrients of GPL were α-tocopherol, linolenic acid, squalene, stigmasterol, and β-amyrin and for GPB were α-tocopherol,
phytol, campesterol, stigmasterol, dictamine, and γ-sitosterol. The percentage inhibition of GPL and GPB extracts at various concentrations was
between 16.57–76.05 and 20.66-78.81 by ABTS assay, 68.24–90.06 and 73.83–96.64% by deoxyribose degradation assay, 4.24–99.98 and 54.81–
99.94 by BSA-fructose model, and 6.31–81.55 and 1.06–74.45 by MMP-1 inhibitory activity, respectively.
Conclusion: Leaves and bark extracts of GP (Retz.) DC. are good sources of important phytonutrients and have the potential in anti-aging property.

Keywords: Glycosmis pentaphylla (Retz) DC, Anti-aging, Phytonutrients, Anti-Glycation, Matrix Mettalloproteinase-1

Link to Academic article: DOI: https://doi.org/10.22159/ijap.2021.v13s1.Y0105

Journal : International Journal of Applied Pharmaceuticsthis, 2021, 13(Special issue 1)

Bibliography     :  Dumrongphuttidecha, T., Khobjai, W., Techaeoi, S., Jarmkom, K., & Thungmungmee, S. (2021). Phytonutrient screening by gas chromatography–mass spectrometry and anti-aging properties of glycosmis pentaphylla (Retz.) dc. (som-chuen) extracts. International Journal of Applied Pharmaceuticsthis, 13(Special Issue 1), 55–58. Retrieved from https://doi.org/10.22159/ijap.2021.v13s1.Y0105