In vitro antiplatelet and anticoagulant activity of indigenous vegetables from Southern Thailand (2021)
Title : In vitro antiplatelet and anticoagulant activity of indigenous vegetables from Southern Thailand
Researcher : Sukati, S., Khobjai, W.
Department :
Abstract : Objective: Epidemiological studies have indicated that diets rich in fruits and vegetables help reduce the risk of cardiovascular diseases (CVDs). However, data about the antithrombotic activity of local vegetables is rare. The objective of this study was to evaluate antiplatelet and anticoagulant activity in indigenous vegetables with high phenolic compounds collected from Southern Thailand.
Methods: Five selected indigenous vegetables were crudely extracted by distilled water and 80% methanol. The extracts were screened for in vitro antiplatelet and anticoagulant activity at a concentration of 10 μg/μl. The antiplatelet activity was measured by inhibition of platelet adhesion to collagen and thrombin-induced platelet aggregation, while the anticoagulant activity was assessed by the prothrombin time (PT) and activated partial thromboplastin time (APTT) tests.
Results: Among the selected vegetables, the extracts of mon-pu (Glochidion perakense Hook.f.) and young cashew leaves (Anacardium occidentale L.) showed high antithrombotic properties. The highest antithrombotic activity was observed in the methanolic extract of mon-pu, which showed
92.79±0.78% of platelet adhesion inhibition, 102.9±1.53% of platelet aggregation inhibition, and a prolonged APTT assay (48.92±0.94 s). The prolonged APTT but normal PT results suggested that the extract could affect factors VIII, IX, XI, and XII of the intrinsic coagulation pathway.
Conclusion: Our findings demonstrated antiplatelet and anticoagulation properties of indigenous vegetables from Southern Thailand. The multipotential effects of mon-pu extracts on antithrombosis evidently suggest that mon-pu can be considered as an excellent nutraceutical option in the prevention of thrombosis-related CVDs caused by different mechanisms.
Keywords: Indigenous vegetables, Antiplatelet activity, Anticoagulant activity, Southern Thailand
Link to Academic article: DOI: https://doi.org/10.22159/ijap.2021.v13s1.Y0100
Journal : ,
Bibliography : Sukati, S., & Khobjai, W. (2021). In vitro antiplatelet and anticoagulant activity of indigenous vegetables from Southern Thailand. , Retrieved from https://doi.org/10.22159/ijap.2021.v13s1.Y0100
Infection prevention and control in Asia: Current evidence and future milestones (2017)
Title : Infection prevention and control in Asia: Current evidence and future milestones
Researcher : Apisarnthanarak, A., Mundy, L.M., Tantawichien, T., Leelarasamee, A.
Abstract : The Asia-Pacific region is a geographic source for emerging infectious diseases, including multidrug-resistant (MDR) organisms (MDROs) and pathogens with pandemic potential. Risks for emerging infectious diseases in this geographic region are complex and are presumed to include ecological, socioeconomic, and technological processes favorable to microbial transmission dynamics. In resource-limited settings, relative to resource-adequate settings, there continues to be a paucity of data in support of infection prevention and control, and patient safety interventions to ensure that regional, if not national, healthcare systems work effectively to improve infection prevention and control interventions. In addition, several viral pandemics and annual influenza strains have originated in the Asia-Pacific region, which, together, has global implications for population health.
Keywords: infection prevention, Asia, Asia Pacific, resource-limited setting, healthcare associated infections
Link to Academic article: https://academic.oup.com/cid/article/64/suppl_2/S49/3782667
Journal : , (Supplement 2).
Bibliography : Apisarnthanarak, A., Mundy, L.M., Tantawichien, T., & Leelarasamee, A. (2017). Infection prevention and control in Asia: Current evidence and future milestones. ,
Influence of Whey Protein on Stability of α-Mangostin Entrapped in Alginate/Whey Protein Beads (2018)
Title : Influence of Whey Protein on Stability of α-Mangostin Entrapped in Alginate/Whey Protein Beads
Researcher : Tunyaporn Sirilert, Nattapol Kajonboon and Nattiga Silalai *
Department : ภาควิชาเทคโนโลยีการอาหาร คณะวิทยาศาสตร์ มหาวิทยาลัยสยาม
E-mail : *ผู้ประสานงานหลัก: tunyapornfood@gmail.com
ฐานข้อมูลงานวิจัย มหาวิทยาลัยสยาม : https://e-research.siam.edu/kb/influence-of-whey-protein-on-stability/
Link to article: Science & Technology Asia, 23(2), 29–36. https://ph02.tci-thaijo.org/index.php/SciTechAsia/article/view/131198
Journal : Science & Technology Asia / in Scopus
Bibliography : Sirilert, T., Kajonboon, N., & Silalai, N. (2018). Influence of Whey Protein on Stability of α-Mangostin Entrapped in Alginate/Whey Protein Beads. Science & Technology Asia, 23(2), 29–36. https://ph02.tci-thaijo.org/index.php/SciTechAsia/article/view/131198
International links between Streptococcus pneumoniae vaccine serotype 4 sequence type (ST) 801 in Northern European shipyard outbreaks of invasive pneumococcal disease (2022)
Title : International links between Streptococcus pneumoniae vaccine serotype 4 sequence type (ST) 801 in Northern European shipyard outbreaks of invasive pneumococcal disease
Researcher : R.A. Gladstone, L. Siira, O.B. Brynildsrud, D.F. Vestrheim, P. Turner, S.C. Clarke, S. Srifuengfung, R. Ford, D. Lehmann, E. Egorova, E. Voropaeva, G. Haraldsson, K.G. Kristinsson, L. McGee, R.F. Breiman, S.D. Bentley, C.L. Sheppard, N.K. Fry, J. Corander, M. Toropainen, A. Steens and The Global Pneumococcal Sequencing Consortium
Link to article: Vaccines, Volume 40, Issue 7, 11 February 2022, Pages 1054-1060 https://doi.org/10.1016/j.vaccine.2021.10.046
Journal : Vaccines / in Scopus
Citation : Gladstone R.A., Siira L., Brynildsrud O.B., Vestrheim D.F., Turner P., Clarke S.C., Srifuengfung S.,… Wolteral N. (2022). International links between Streptococcus pneumoniae vaccine serotype 4 sequence type (ST) 801 in Northern European shipyard outbreaks of invasive pneumococcal disease. Vaccine, 40(7), 1054-1060. https://doi.org/10.1016/j.vaccine.2021.10.046
ฐานข้อมูลงานวิจัย มหาวิทยาลัยสยาม : https://e-research.siam.edu/kb/international-links-between-streptococcus/
Invasive Streptococcus Pneumoniae Serotype 19A in Thailand (2008-2018)(2022)
Title : Invasive Streptococcus Pneumoniae Serotype 19A in Thailand (2008-2018)
Researcher : Piriyaporn Chongtrakool, Unchalee Puangprasart, Wanatpreeya Phongsamart, Chanwit Tribuddharat, Chalermsri Pummangura and Somporn Srifuengfung
Link to article: The Southeast Asian Journal of Tropical Medicine and Public Health, Volume 53, No.1, January 2022, Pages 73-90. https://journal.seameotropmednetwork.org/index.php/jtropmed/article/view/581
Journal : The Southeast Asian Journal of Tropical Medicine and Public Health / Scopus
Citation : Chongtrakool P., Puangprasart U., Phongsamart W., Tribuddharat C., Pummangura C., Srifuengfung S. (2022). Invasive streptococcus pneumoniae serotype 19A in Thailand (2008-2018). TheSoutheast Asian Journal of Tropical Medicine and Public Health, 53(1), 73-90. https://journal.seameotropmednetwork.org/index.php/jtropmed/article/view/581
ฐานข้อมูลงานวิจัย มหาวิทยาลัยสยาม : https://e-research.siam.edu/kb/invasive-streptococcus-pneumoniae-serotype-19a/
Isolation and Antibiotic Susceptibility Profile of Salmonella spp. from Patients in a Tertiary Care Hospital in Thailand (2023)
Title : Isolation and Antibiotic Susceptibility Profile of Salmonella spp. from Patients in a Tertiary Care Hospital in Thailand
Researcher : Piriyaporn Chongtrakool, Preeyanuch Wangleotsakulchai, Tippavan Tabboon, Huttaya Thuncharoon, Chalermsri Pummangura, Dararat Samretwit, Thitiya Yungyuen, Premwadee Khowwigkai, Tanate Suttisaewan & Somporn Srifuengfung
Link to article : Journal of the Medical Association of Thailand, Volume 106, Issue 2, February 2023, Pages 200-206. https://doi.org/10.35755/jmedassocthai.2023.02.13784
Journal : Journal of the Medical Association of Thailand / in Scopus
Citation : Chongtrakool P., Wangleotsakulchai P., Tabboon T., Thuncharoon H., Pummangura C., Samretwit D., Yungyuen T., Khowwigkai P., Suttisaewan T., & Srifuengfung S. (2023). Isolation and antibiotic susceptibility profile of salmonella spp. from patients in a tertiary care hospital in Thailand. Journal of the Medical Association of Thailand, 106(2), 200-206. https://doi.org/10.35755/jmedassocthai.2023.02.13784
ฐานข้อมูลงานวิจัย มหาวิทยาลัยสยาม : https://e-research.siam.edu/kb/isolation-and-antibiotic/
Isolation and Antimicrobial Susceptibility Testing of Haemophilus influenzae in a Tertiary Care Hospital, a 6-Year Study (2016 to 2021) (2022)
Title : Isolation and Antimicrobial Susceptibility Testing of Haemophilus influenzae in a Tertiary Care Hospital, a 6-Year Study (2016 to 2021)
Researcher : Piriyaporn Chongtrakool, Patcharee Choochur, Huttaya Thuncharoon, Mraeyttwinite Srifuengfung, Boonta Sawatdijaroongrat, Chalermsri Pummangura, Dararat Samretwit & Somporn Srifuengfung
Link to article : Journal of the Medical Association of Thailand, Volume 105, Issue 4, 15 March 2022 , pages 335-339. https://doi.org/10.35755/jmedassocthai.2022.04.13296
Journal : Journal of the Medical Association of Thailand / in Scopus
Citation : Chongtrakool P., Choochur P., Thuncharoon H., Srifuengfung M., Sawatdijaroongrat B., Pummangura C., Samretwit D., & Srifuengfung S. (2022). Isolation and antimicrobial susceptibility testing of Haemophilus influenzae in a tertiary care hospital, a 6-year study (2016 to 2021). Journal of the Medical Association of Thailand, 105(4), 335-339. https://doi.org/10.35755/jmedassocthai.2022.04.13296
ฐานข้อมูลงานวิจัย มหาวิทยาลัยสยาม : https://e-research.siam.edu/kb/isolation-and-antimicrobial-susceptibility/
Lacosamide dosing in patients receiving continuous renal replacement therapy (2023)
Title : Lacosamide dosing in patients receiving continuous renal replacement therapy
Researcher : Weerachai Chaijamorn, Sathian Phunpon, Thanompong Sathienluckana, Taniya Charoensareerat, Sutthiporn Pattharachayakul, Dhakrit Rungkitwattanakul and Nattachai Srisawat
Link to article: Journal of Intensive Care, Volume 11, Issue 50, pages 1-9. https://doi.org/10.1186/s40560-023-00700-4
Citation : Chaijamorn W, Phunpon S, Sathienluckana T, Charoensareerat T, Pattharachayakul S, Rungkitwattanakul D and Srisawat N. (2023). Lacosamide dosing in patients receiving continuous renal replacement therapy. Journal of Intensive Care, 11(50), 1-9. https://doi.org/10.1186/s40560-023-00700-4
Journal : Journal of Intensive Care / in Scopus
ฐานข้อมูลงานวิจัย มหาวิทยาลัยสยาม : https://e-research.siam.edu/kb/lacosamide-dosing-in-patients/
Late onset of serious agomelatine-induced liver injury (2021)
Title : Late onset of serious agomelatine-induced liver injury
Researcher : Maytinee Srifuengfung, Somporn Srifuengfung, Chalermsri Pummangura
Link to article: Sleep Medicine Vol.2021 No.86 p. 122. https://doi.org/10.1016/j.sleep.2021.06.031
Journal : Sleep Medicine / in Scopus
Citation : Srifuengfung M., Srifuengfung S. & Pummangura C. (2021). Late onset of serious agomelatine-induced liver injury. Sleep Medicine, 2021(86), 122. https://doi.org/10.1016/j.sleep.2021.06.031
ฐานข้อมูลงานวิจัย มหาวิทยาลัยสยาม : https://e-research.siam.edu/kb/late-onset-of-serious/
Levetiracetam dosing in patients receiving continuous renal replacement therapy (2021)
Title : Levetiracetam dosing in patients receiving continuous renal replacement therapy
Researcher : Weerachai Chaijamorn, Taniya Charoensareerat, Dhakrit Rungkitwattanakul, Sathian Phunpon, Thanompong Sathienluckana, Nattachai Srisawat & Sutthiporn Pattharachayakul
Link to article: Epilepsia Volume 62, Issue9, September 2021, Pages 2151-2158. https://doi.org/10.1111/epi.16971
Citation : Chaijamorn W., Charoensareerat T., Rungkitwattanakul D., Phunpon S., Sathienluckana T., Srisawat N. & Pattharachayakul S. (2021). Levetiracetam dosing in patients receiving continuous renal replacement therapy. Epilepsia, 62(9), 2151-2158. https://doi.org/10.1111/epi.16971
Journal : Epilepsia / in Scopus
ฐานข้อมูลงานวิจัย มหาวิทยาลัยสยาม : https://e-research.siam.edu/kb/levetiracetam-dosing-in-patients/