Synthesis of Benzoazepine Derivatives via Azide Rearrangement and Evaluation of Their Antianxiety Activities (2021)
Title : Synthesis of Benzoazepine Derivatives via Azide Rearrangement and Evaluation of Their Antianxiety Activities
Researcher : Onrapak Reamtong, Sarawut Lapmanee, Jumreang Tummatorn, Nitwaree Palavong, Charnsak Thongsornkleeb, and Somsak Ruchirawat
Department : Faculty of Medicine, Siam University, Bangkok, Thailand
E-mail : sarawut.lap@siam.ed
Link to article : ACS Medicinal Chemistry Letters, 2021, 12(9), 1449–1458. https://doi.org/10.1021/acsmedchemlett.1c00275
Citation : Reamtong, O., Lapmanee, S., Tummatorn, J., Palavong, N., Thongsornkleeb, C., & Ruchirawat, S. (2021). Synthesis of Benzoazepine Derivatives via Azide Rearrangement and Evaluation of Their Antianxiety Activities. ACS Medicinal Chemistry Letters, 12(9), 1449–1458. https://doi.org/10.1021/acsmedchemlett.1c00275
Journal : ACS Medicinal Chemistry Letters / in Scopus
ฐานข้อมูลงานวิจัย มหาวิทยาลัยสยาม : –
Synthesis of carboxymethyl cellulose from rice husk (2021)
Title : Synthesis of carboxymethyl cellulose from rice husk
Researcher : Jarmkom, K., Khobjai, W., Teachaoei, S., Shuwisitkul, D.
Department :
Abstract : Objective: The purpose of this research was to produce carboxymethyl cellulose from rice husk (CMCRH) and used it as a raw material in food or health products.
Methods: Cellulose was extracted from husk rice and converted to CMC (CMCRH) using sodium hydroxide (NaOH) and monochloroacetic acid in isopropanol (C3H8O).
Results: CMCRH was characterized for chemical composition and morphology by scanning electron microscopy. Microscopy analysis showed that chemical composition changes with increasing sodium content (Na-). Likewise, morphology has changed. Physicochemical and viscosity tests showed that were similar properties compare with commercial CMC.
Conclusion: CMC is derived cellulose that is used in products for various applications. RH is an agricultural waste that is carried out to synthesize CMC (CMCRH). Finally, CMCRH has the potential to be used in raw materials in food or health products which biodegradable material.
Keywords: Cellulose, Carboxymethyl cellulose, Rice husk
Link to Academic article: DOI: https://doi.org/10.22159/ijap.2021.v13s1.Y0104
Journal : this,
Bibliography : Jarmkom, K., Khobjai, W., Teachaoei, S., & Shuwisitkul, D. (2021). Synthesis of carboxymethyl cellulose from rice husk. this, Retrieved from https://doi.org/10.22159/ijap.2021.v13s1.Y0104
Synthesis of soluble calcium compound from skipjack tuna bones using edible weak acids (2022)
Title : Synthesis of soluble calcium compound from skipjack tuna bones using edible weak acids
Researcher : Chakkapat Aenglong, Yu-Ming Wang, Maruj Limpawattana, Wanida Sukketsiri, Qing-Juan Tang, Wanwimol Klaypradit, Soraya Kerdpiboon
Department : สำนักอธิการบดี มหาวิทยาลัยสยาม
E-mail : maruj.lim@siam.edu
ฐานข้อมูลงานวิจัย มหาวิทยาลัยสยาม : –
Link to article: LWT, 2022, 162, 113460. https://doi.org/10.1016/j.lwt.2022.113460
Journal : LWT / in Scopus
Bibliography : Aenglong, C., Wang, Y. M., Limpawattana, M., Sukketsiri, W., Tang, Q. J.,Klaypradit, W., & Kerdpiboon, S. (2022). Synthesis of soluble calcium compound from skipjack tuna bones using edible weak acids. LWT, 162, 113460. https://doi.org/10.1016/j.lwt.2022.113460
Thailand’s dual education system: A way forward (2017)
Title : Thailand’s dual education system: A way forward
Researcher : รศ.ดร. จอมพงศ์ มงคลวนิช Jomphong Mongkhonvanit
Department : รองศาสตราจารย์ประจำสาขาวิชาการบริหารหารศึกษา บัณฑิตวิทยาลัยศึกษาศาสตร์ มหาวิทยาลัยสยาม กรุงเทพมหานคร 10160
E-mail :
ฐานข้อมูลงานวิจัย มหาวิทยาลัยสยาม : –
Link to article: Higher Education, Skills and Work-based Learning, 2017, 7(2), pp. 155–167. https://doi.org/10.1108/HESWBL-09-2016-0067
Publication: Higher Education, Skills and Work-based Learning / in Scopus
Bibliography : Mongkhonvanit, J. (2017), “Thailand’s dual education system: a way forward”, Higher Education, Skills and Work-Based Learning, 7(2), 155-167. https://doi.org/10.1108/HESWBL-09-2016-0067
The analgesic efficacy of anterior femoral cutaneous nerve block in combination with femoral triangle block in total knee arthroplasty: a randomized controlled trial(2021)
Title : The analgesic efficacy of anterior femoral cutaneous nerve block in combination with femoral triangle block in total knee arthroplasty: a randomized controlled trial
Researcher : Kampitak, W., Tanavalee, A., Tansatit, T., …Songborassamee, N., Vichainarong, C.
Abstract : Background: Ultrasound-guided femoral triangle block (FTB) can provide motor-sparing anterior knee analgesia. However, it may not completely anesthetize the anterior femoral cutaneous nerve (AFCN). We hypothesized that an AFCN block (AFCNB) in combination with an FTB would decrease pain during movement in the immediate 12 h postoperative period compared with an FTB alone.
Methods: Eighty patients scheduled to undergo total knee arthroplasty were randomized to receive either FTB alone (FTB group) or AFCNB with FTB (AFCNB + FTB group) as part of the multimodal analgesic regimen. The primary outcome was pain during movement at 12 h postoperatively. Secondary outcomes included numeric rating scale (NRS) pain scores, incidence of surgical incision site pain, intravenous morphine consumption, immediate functional performance, patient satisfaction, and length of hospital stay.
Results: The NRS pain scores on movement 12 h postoperatively were significantly lower in the AFCNB + FTB group than in the FTB group (mean difference: –2.02, 95% CI: –3.14, –0.89, P < 0.001). The incidence of pain at the surgical incision site at 24 h postoperatively and morphine consumption within 48 h postoperatively were significantly lower (P < 0.001), and quadriceps muscle strength at 0° immediately after surgery was significantly greater in the AFCNB + FTB group (P = 0.04).
Conclusions: The addition of ultrasound-guided AFCNB to FTB provided more effective analgesia and decreased opioid requirement compared to FTB alone after total knee arthroplasty and may enhance immediate functional performance on the day of surgery.
Link to Academic article: DOI: https://doi.org/10.4097/kja.21120
Journal : ,
Bibliography : Kampitak, W., Tanavalee, A., Tansatit, T., Ngarmukos, S., Songborassamee, N., & Vichainarong, C. (2021). The analgesic efficacy of anterior femoral cutaneous nerve block in combination with femoral triangle block in total knee arthroplasty: a randomized controlled trial. ,
The Application of Ethnographic Techniques for Community-Based Tourism Research
Title : The Application of Ethnographic Techniques for Community-Based Tourism Research
Researcher : Nantira Pookhao and Yuvarin Sripan
Department : Faculty of Liberal Arts , Siam University, Bangkok, Thailand
E-mail : nantira.sand.pookhao@gmail.com
Abstract : Tourism generates massive income for Thailand. Using tourism as an economic goal has both positive and negative impacts on local community located in or near tourism destination. To mitigate negative impacts of tourism, local people should participate in its planning, management and operation. Participation of local people in the process of tourism development is to promote the community-based tourism (CBT) initiation. CBT is expected to lead to the balance of ecological conservation and development by concentrating on the quality of life of the local people. It is a new tourism phenomenon in Thai rural society that endeavours for community self reliant practice. Operating CBT, community members are associated with and cannot be separated from the tourism activities and touristic process, as active rather than passive actors. Given that tourism activities are hardly distinguished from their local way of life and CBT is associated with participation towards empowerment and local sociocultural realm, ethnographic technique is a considerable choice to conduct a CBT research. It enables indepth and holistic view in relation to the impact of power and the processes of globalization on local socioculture and the findings can be used for further tourism development towards sustainability.
Keywords : Community-based tourism, local participation, research method, ethnography, Thailand
Download PDF: The Application of Ethnographic Techniques for Community-Based Tourism Research
Proceeding : การประชุมวิชาการระดับชาติ สมาคมสถาบันอุดมศึกษาเอกชนแห่งประเทศไทย ประจำปี 2560 วันที่ 25 พฤษภาคม 2560 มหาวิทยาลัยรัตนบัณฑิต APHEIT Conference 2017
Link to Proceeding: http://apheitconference.siam.edu/index.php/en/proceedings-2012-2016
Bibliography : Nantira Pookhao & Yuvarin Sripan. (2560). The application of ethnographic techniques for community-based tourism research. In Proceedings of PHEIT Conference 2017 (pp. 1036-1046). Bangkok, Thailand.
The crest injection technique for glabellar line correction and the paracentral artery (2021)
Title : The crest injection technique for glabellar line correction and the paracentral artery
Researcher : Tansatit, T., Uruwan, S., Rungsawang, C.
Abstract : The glabella is a zone that carries a high risk of blindness after performing filler injections. The arteries beneath the glabellar lines were investigated by meticulous dissections in 30 geriatric embalmed cadavers with latex injections into the arterial system. The results showed that the supratrochlear artery, a direct branch of the ophthalmic artery, ascended from the muscular layer of the medial eyebrow along the medial canthal vertical line of the intercanthal vertical zone (53 in 60 hemifaces, or 88%). The dominant single paracentral artery from the radix artery was found within the radix vertical zone (eight out of 30 glabellae, or 27%). Among these, the dominant paracentral artery was near the midline in two cadavers and arose along the radix vertical line in six cadavers. The dominant paracentral artery may be the cause of ocular complications during injections of glabellar lines between the medial eyebrows, especially at the radix vertical lines. The supratrochlear artery might cause ocular complications when an injection is performed close to the medial eyebrows. Pinching to create a skin crest and evert glabellar line for a precise injection is recommended to temporarily occlude the paracentral artery.
Link to Academic article: DOI: 10.1097/GOX.0000000000003982
Journal : ,
Bibliography : Tansatit, T., Uruwan, S. & Rungsawang, C.,(2021). The crest injection technique for glabellar line correction and the paracentral artery. , 9(12)
The effectiveness of the modified mueller–hillis maneuver in predicting successful vaginal delivery in late active phase of first stage of labor (2019)
Title : The effectiveness of the modified mueller–hillis maneuver in predicting successful vaginal delivery in late active phase of first stage of labor
Researcher : Kovavisarach, E., Jongfuangprinya, K.
Abstract : Background: Cephalopelvic disproportion is one of the most common indications for cesarean section. Abnormal labor patterns have been used to identify this condition for many years, but early diagnosis is sometimes quite difficult.
Objective: To determine the accuracy of the modified Mueller-Hillis maneuver in predicting successful vaginal delivery in the late active phase of the first stage of labor.
Materials and Methods: From July 1st 2009 to August 31st 2010, a diagnostic test was performed of pregnant women admitted to the Labor Room in Rajavithi Hospital who met the following inclusion criteria: singleton pregnancy; labor pain, vertex presentation, and gestational age between 37 and 42 weeks. The exclusion criteria were medical or obstetric complications, or induction of labor with uterotonic agent. The modified Mueller-Hillis maneuver was performed by a single operator applying fundal pressure and assessing the descent of the fetal head in the late active phase of the first stage of labor (cervical dilatation >8 cm). Descent of the fetal head of 1 cm or more was interpreted as a positive result, and successful vaginal delivery was defined as spontaneous vaginal delivery without instrumentation.
Results: Two hundred and twenty-six women were enrolled, 214 of whom had positive results, with 212 successful vaginal deliveries, one case of delivery by forceps extraction, and another of cesarean delivery. Of the 12 cases with negative results, 4 had successful vaginal delivery while the others were delivered by cesarean section. The sensitivity, specificity, accuracy, positive and negative predictive values of the positive test were 98.2%, 88.9%, 97.8%, 99.5%, and 66.7%, respectively.
Conclusion: The modified Mueller-Hillis technique performed in the late active phase of the first stage of labor yielded excellent results in terms of diagnostic parameters such as sensitivity, specificity, accuracy and positive predictive values, but the negative predictive values were only fair.
Keywords: Modified Mueller-Hillis maneuver, Vaginal delivery, First stage of labor
Link to Academic article: http://www.jmatonline.com/index.php/jmat/article/view/10454
Journal : ,
Bibliography : Kovavisarach, E., & Jongfuangprinya, K. (2019). The effectiveness of the modified mueller–hillis maneuver in predicting successful vaginal delivery in late active phase of first stage of labor.
The efficacy and safety of andrographis paniculata extract for the treatment of acute nonspecific upper respiratory tract infections: A randomized double blind placebo controlled trial (2021)
Title : The efficacy and safety of andrographis paniculata extract for the treatment of acute nonspecific upper respiratory tract infections: A randomized double blind placebo controlled trial
Researcher : Leelarasamee, A., Suankratay C , Hunnangkul S , Udompunturak S , Krittayaphong R , Poonsrisawat J , Wongsakorn N , Ittipanitphong C , Sirimai S , Prakairoongthong P , Rattanamaneekorn S , Chaicharoenpong K
Department :
Abstract : Background: The efficacy and safety of Andrographis paniculata (Burn.f.) Wall. ex Nees in the treatment of acute nonspecific upper respiratory tract infection (NS-URI) are still less clear due to the diversity of herbal preparations, dosages, and few large clinical trials. The authors aimed to investigate the therapeutic efficacy and safety of the crude extract from A. paniculata in acute NS-URI.
Materials and Methods: Patients aged 18 to 60 years old from government hospitals, with acute NS-URI were enrolled between January 2018 and August 2019. Drug allocation was randomized in block of six. The crude extract of A. paniculata was packed in capsules containing 20 mg of andrographolide andgiven thrice daily for four days. The placebo capsules were physically identical. Ten tablets of paracetamol were also given as symptom-rescue drug. They were followed at days 4 to 7, and 14 to 30.
Results: Eight hundred sixty-two patients were enrolled between January 2018 and August 2019. Thirty-three patients withdrew from the study, therefore, 829 patients remained in the final analysis. Four hundred nineteen cases (50.5%) received the crude extract, and 410 cases (49.5%) received the placebo. The demographic data, clinical manifestation, and laboratory findings at the enrollment were similar in both groups. At the first follow-up, the rates of severity of each and combined symptoms decreased similarly, and almost all patients felt much better or recovered on day 7. Paracetamol was used by 205 (48.9%) and 185 (45.1%) patients in the experimental and control groups, respectively, and about three tablets taken in each group. Patient satisfaction rates were also similar in both groups. Adverse effects were mild and self-limited in 18 (4.3%) and 9 (2.2%) patients in the experimental and control groups, respectively.
Conclusion: The therapeutic efficacy of the crude extract or active ingredient from A. paniculata for acute NS-URI was not confirmed. Both groups showed similarly mild and few adverse drug reactions.Trial registration: The present study protocol was registered at the Thai Clinical Trials Registry (TCTR 20170329002; date: March 26, 2017).
Keywords: Andrographis paniculata; Andrographolide; Acute nonspecific upper respiratory tract infections; Common cold; Pharyngitis; URI
Link to Academic article: doi.org/10.35755/jmedassocthai.2021.07.13037
Journal : this,
Bibliography : Leelarasamee, A., Suankratay, C., Hunnangkul, S., Udompunturak, S., Krittayaphong, R., Poonsrisawat, J.,…Chaicharoenpong, K. (2021). The efficacy and safety of andrographis paniculata extract for the treatment of acute nonspecific upper respiratory tract infections: A randomized double blind placebo controlled trial.
The feasibility determination of risky severe complications of arterial vasculature regarding the filler injection sites at the tear trough (2018)
Title : The feasibility determination of risky severe complications of arterial vasculature regarding the filler injection sites at the tear trough
Researcher : Jitaree, B., Phumyoo, T., Uruwan, S., …McCormick, L., Tansatit, T.
Abstract : Background: The tear trough is a significant sign of periorbital aging and has usually been corrected with filler injection. However, the arterial supply surrounding the tear trough could be inadvertently injured during injection; therefore, this study aimed to evaluate the nearest arterial locations related to the tear trough and investigate the possibility of severe complications following filler injection.
Methods: Thirty hemifaces of 15 Thai embalmed cadavers were used in this study.
Results: The artery located closest to both the inferior margin (TT1) and mid-pupil level (TT2) of the tear trough was found to be the palpebral branch of the infraorbital artery. Furthermore, at 0.5 mm along the tear trough from the medial canthus (TT3), the angular artery was identified, which was found to be a branch of the ophthalmic artery. The artery at TT1 and TT2 was located beneath both the zygomaticus major and the orbicularis oculi muscles. The distances from TT1 to the artery were measured as follows: laterally, 2.79 ± 1.08 mm along the x axis; and inferiorly, 2.88 ± 1.57 mm along the y axis. For the TT2, the artery was located inferomedially from the landmark of 4.65 ± 1.83 mm along the x axis and 7.13 ± 3.99 mm along the y axis. However, the distance along the x axis at TT3 was located medially as 4.00 ± 2.37 mm.
Link to Academic article: DOI: 10.1097/PRS.0000000000004893
Journal : , 2018, 142(5).
Bibliography : Jitaree, B., Phumyoo, T., Uruwan, S., Sawatwong, W., McCormick, L., & Tansatit, T. (2018). The feasibility determination of risky severe complications of arterial vasculature regarding the filler injection sites at the tear trough.