Comparison of the Effectiveness and Safety of Clozapine Between Once-Daily and Divided Dosing Regimen in Patients With Treatment-Resistant Schizophrenia (2023)

Title           : Comparison of the Effectiveness and Safety of Clozapine Between Once-Daily and Divided Dosing Regimen in Patients With Treatment-Resistant Schizophrenia

Researcher       :  Thanompong Sathienluckana, Thaksin Jansing,Supakan Srisuriyakamon, Aunchalee thonkhunthod, Parsiri Sangsuwanto, Pholphat Losatiankij and Suttha Supanya

Link to article: Annals of Pharmacotherapy, 2023 Sep 24;10600280231201708. https://doi.org/10.1177/10600280231201708

Citation  : Sathienluckana T, Jansing T, Srisuriyakamon S, Thonkhunthod A, Sangsuwanto S, Losatiankij P and Supanya S. (2023). Comparison of the effectiveness and safety of clozapine between once-daily and divided dosing regimen in patients with treatment-resistant schizophrenia. Annals of Pharmacotherapy, 10600280231201708. https://doi.org/10.1177/10600280231201708


Journal : Annals of Pharmacotherapy  / in Scopus


ฐานข้อมูลงานวิจัย มหาวิทยาลัยสยาม  : https://e-research.siam.edu/kb/comparison-of-the-effectiveness/

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Complete Genome Sequence of Neisseria gonorrhoeae Multilocus Sequence Type ST7363 Isolated from Thailand (2021)

Title           : Complete Genome Sequence of Neisseria gonorrhoeae Multilocus Sequence Type ST7363 Isolated from Thailand

Researcher       : Thitima Cherdtrakulkiat, Thidathip Wongsurawat, Piroon Jenjaroenpun, Sawannee Sutheeworapong, Wanna Leelawiwat, Joseph V. Woodring, Eileen F. Dunne, John R. Papp, Somporn Srifuengfung and Chanwit Tribuddharati

Link to article: Microbiology Resource Announcements Vol.10 No.e00573-21 Page. 1-4. https://doi.org/10.1128/mra.00573-21


Journal : Microbiology Resource Announcements / in Scopus


Citation : Cherdtrakulkiat T., Wongsurawat T., Jenjaroenpun P., Sutheeworapong S., Leelawiwat W., Woodring, Joseph V. , Dunne, Eileen F. , Papp, John R. Srifuengfung S. &  Tribuddharati, C. (2021). Complete genome sequence of neisseria gonorrhoeae multilocus sequence type ST7363 isolated from Thailand. Microbiology Resource Announcements, 10(e00573-21), 1-4. https://doi.org/10.1128/mra.00573-21


ฐานข้อมูลงานวิจัย มหาวิทยาลัยสยาม      :  https://e-research.siam.edu/kb/complete-genome-sequence-of-neisseria-gonorrhoeae/

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Compound Heterozygous PGM3 Mutations in a Thai Patient with a Specific Antibody Deficiency Requiring Monthly IVIG Infusions (2020)

Title           :  Compound Heterozygous PGM3 Mutations in a Thai Patient with a Specific Antibody Deficiency Requiring Monthly IVIG Infusions

Researcher       : Clin.Prof.Suwat Benjaponpitak 

Department     : Faculty of Medicine, Siam University, Bangkok, Thailand

E-mail                : med@siam.edu

Link to Academic articleDOI: 10.1007/s10875-019-00693-6


Journal :  Journal of Clinical Immunology  Vol. 40, No. 1, 2020


Bibliography     : Ittiwut, C., Manuyakorn, W., Tongkobpetch, S., Benjaponpitak, S., Fisher, M. R., Milner, J. D., Lyons, J. J., Suphapeetiporn, K., & Shotelersuk, V. (2020, January). Compound Heterozygous PGM3 Mutations in a Thai Patient with a Specific Antibody Deficiency Requiring Monthly IVIG Infusions. J Clin Immunol, 40(1), 227-231. doi: 10.1007/s10875-019-00693-6. Epub 2019 Nov 9. PMID: 31707513.


 

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Construction of the Short-Form Thai-Home Fall Hazard Assessment Tool (Thai-HFHAT-SF) and Testing Its Validity and Reliability in the Elderly (2022)

Title           :  Construction of the Short-Form Thai-Home Fall Hazard Assessment Tool (Thai-HFHAT-SF) and Testing Its Validity and Reliability in the Elderly

Researcher       Charupa Lektip, Sarawut Lapmanee, Rewwadee Petsirasan, Kanda Chaipinyo, Saifon Lektip, and Jiraphat Nawarat.

Department     : Faculty of Medicine, Siam University, Bangkok, Thailand

E-mail                : sarawut.lap@siam.ed

Link to article : International Journal of Environmental Research and Public Health, 2022,19(9), 5187. https://doi.org/10.3390/ijerph19095187

Citation  :  Lektip, C., Lapmanee, S., Petsirasan, R., Chaipinyo, K., Lektip, S., & Nawarat, J. (2022). Construction of the Short-Form Thai-Home Fall Hazard Assessment Tool (Thai-HFHAT-SF) and Testing Its Validity and Reliability in the Elderly. International Journal of Environmental Research and Public Health, 19(9), 5187. https://doi.org/10.3390/ijerph19095187


Journal : International Journal of Environmental Research and Public Health / in Scopus


ฐานข้อมูลงานวิจัย มหาวิทยาลัยสยาม  :

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Conventional and microwave-assisted extraction for bioactive compounds from dried coffee cherry peel by-products and antioxidant activity of the aqueous extracts (2020)

Title              :  Conventional and microwave-assisted extraction for bioactive compounds from dried coffee cherry peel by-products and antioxidant activity of the aqueous extracts

Researcher       : Thaiphanit, S.Wedprasert, W.Srabua, A.

Department     : ภาควิชาเทคโนโลยีการอาหาร คณะวิทยาศาสตร์ มหาวิทยาลัยสยาม

E-mail                : somruedee.tha@siam.edu

ฐานข้อมูลงานวิจัย มหาวิทยาลัยสยาม: https://e-research.siam.edu/kb/conventional-and-microwave-assisted-extraction-for-bioactive-compounds-from-dried-coffee-cherry-peel-by-products-and-antioxidant-activity-of-the-aqueous-extracts/


Link to article: ScienceAsia, 2020, 46 S(1), pp. 12–18. https://www.scienceasia.org/content/viewabstract_progress.php?ms=11118


Journal :  ScienceAsia / in Scopus


Bibliography     :  Somruedee Thaiphanit, Warintorn Wedprasert and Aristha Srabua. (2020). Conventional and microwave-assisted extraction for bioactive compounds from dried coffee cherry peel by-products and antioxidant activity of the aqueous extracts. ScienceAsia, 46S(1), 12-18.


 

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Correlation between transperineal and transvaginal sonography in cervical length measurement among normal thai pregnant women at 16 to 24 weeks of gestation (2018)

Title           : Correlation between transperineal and transvaginal sonography in cervical length measurement among normal thai pregnant women at 16 to 24 weeks of gestation

Researcher       : Kovavisarach, E.Kedthong, R.

Abstract            : Background: Currently, cervical length is generally measured by transvaginal sonography (TVS) to predict preterm labor. Transperineal sonography (TPS) has been proposed as an alternative modality to TVS.
Objective:
To compare cervical length measurements and pain scores of TPS and TVS in normal Thai pregnant women
Material and Method:
A total of 40 normal Thai pregnant singleton women were enrolled at the antenatal clinic, Rajavithi Hospital between 1st December 2014 and 28th February 2015 at 16 to 24 weeks of gestation. Patients were excluded if they had history of and proved rupture of membranes, body mass index (BMI) >30 kg/m2, antepartum hemorrhage, or mass at perineum. The TPS and TVS techniques for cervical length measurement were performed in all cases by a single researcher (RK). Visual analog scale (VAS) score was used to assess the pain score (total = 10).
Results:
Mean cervical lengths measured by TVS were slightly greater than those found using TPS (37.80 mm and 35.73 mm, respectively). The Pearson’s correlation coefficient between the two methods was 0.746, p<0.01. Mean pain scores determined by VAS score in TPS and TVS were 0.15 and 0.03, respectively (p = 0.02). The number of people whose VAS score was zero was similar with both methods (87.2% and 71.8%, respectively) (p = 0.095).
Conclusion: TPS could be used as an alternative method of TVS to assess CL in normal Thai pregnant women at 16 to 24 weeks of gestation because of its good correlation coefficient and lower pain levels.

Keywords: Cervical length, Transperineal sonography, Transvaginal sonography


Link to Academic article: http://www.jmatonline.com/index.php/jmat/article/view/9089


Journal : Journal of the Medical Association of Thailand2018, 101(Suppl.2)


Bibliography     : Kovavisarach, E., & Kedthong, R. (2018). Correlation between transperineal and transvaginal sonography in cervical length measurement among normal thai pregnant women at 16 to 24 weeks of gestation. Journal of the Medical Association of Thailand, 101(Suppl.2), S19–S23.


 

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Creating and Collecting e-Learning Event Logs to Analyze Learning Behavior of Students through Process Mining (2023)

 

Title              :  Creating and Collecting e-Learning Event Logs to Analyze Learning Behavior of Students through Process Mining

Researcher       : Nammakhunt, A.Porouhan, P.Premchaiswadi, W.
Department      : Doctor of Philosophy Program in Information Technologyy, Graduate School, Siam University

E-mail                 :

ฐานข้อมูลงานวิจัย มหาวิทยาลัยสยาม            :  https://e-research.siam.edu/kb/creating-and-collecting-e-learning/

Link to article:  International Journal of Information and Education Technology, 2023, 13(2), pp. 211–222, 1798. https://doi.org/10.18178/ijiet.2023.13.2.1798

Publication: International Journal of Information and Education Technology / in Scopus

Bibliography     : Nammakhunt, A.Porouhan, P.Premchaiswadi, W. (2023). Creating and Collecting e-Learning Event Logs to Analyze Learning Behavior of Students through Process Mining. International Journal of Information and Education Technology, 13(2), 211–222, 1798. https://doi.org/10.18178/ijiet.2023.13.2.1798

 


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De novo food allergy in pediatric liver transplantation recipients (2018)

Title           :  De novo food allergy in pediatric liver transplantation recipients

Researcher       : Clin.Prof.Suwat Benjaponpitak 

Department     : Faculty of Medicine, Siam University, Bangkok, Thailand

E-mail                : med@siam.edu

Abstract            :  Background: Food allergy (FA) prevalence is increasing in pediatric liver transplantation (LT). However, the clinical course is still limited.

Objective: This retrospective cohort study aimed to identify the prevalence, risk factors, and the natural history of de novo FA in children post LT.

Methods: Medical records of pediatric LT recipients from Jan 2001 – Dec 2014 were reviewed. De novo FA was diagnosed by symptoms after exposure to culprit food occurring after LT, and improvement after diet elimination. FA was confirmed if reproduced symptoms after re-challenge or documented sensitization or indicated gastrointestinal eosinophilia.

Results: Among 46 post LT children, 54.3% developed de novo FA at a median time of 12.2 months [Interquartile range (IQR) 6.2, 21.3 months] post LT. The confirmed FA was 39.1%. Gastrointestinal symptom was the most common manifestation followed by skin, anaphylaxis, and others. Culprit foods were cow’s milk, shellfish, egg, wheat, soybean, peanut, coconut, fish and monosodium glutamate. The risk factors of FA were transplantation during age below 2 years [hazard ratio (HR), 2.62; 95% confidence interval (CI), 1.04 – 6.59; p = 0.03), atopic history in family (HR, 5.67; 95% CI, 1.33 – 24.12; p = 0.01), and Epstein-Barr (EBV) viremia (HR, 2.39; 95% CI, 1.02 – 5.63; p = 0.04).

Conclusions: de novo FA in pediatric LT is not uncommon. Age at LT younger than 2 years, family history of atopy, and EBV viremia are associated with developing FA. Development of tolerance after elimination culprit diets for 3 years is similar to general population.

Key words: Food allergy, liver transplantation, tolerance, outgrown, de novo food allergy

Link to Academic article: DOI: 10.12932/AP-080217-0007


Journal : Asian Pacific journal of allergy and immunology 


Bibliography     : Sinitkul, R., Manuyakorn, W., Kamchaisatian, W., Vilaiyuk, S., Benjaponpitak, S., Lertudompholwanit, C., & Treepongkaruna, S. (2018, September). De novo food allergy in pediatric liver transplantation recipients. Asian Pac J Allergy Immunol, 36(3), 166-174. doi: 10.12932/AP-080217-0007. PMID: 29161056.


 

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Designing electrospun shellac nanofibers with mupirocin using the Box-Behnken approach for topical wound care (2022)

Title           : Designing electrospun shellac nanofibers with mupirocin using the Box-Behnken approach for topical wound care

Researcher       Nawinda Chinatangkul, Sirikarn Pengon,Wantanwa Krongrawa, Siraprapa Chansatidkosol, Chutima Limmatvapirat and Sontaya Limmatvapirat

Link to article: Journal of Drug Delivery Science and Technology, Volume 76, Issue 103720, 31 August 2022, Pages 1-8. https://doi.org/10.1016/j.jddst.2022.103720

Citation  : Chinatangkul N., Pengon S., Chatsuwan T., Krongrawa W., Chansatidkosol S., Limmatvapirat C. and Limmatvapirat S. (2022). Designing electrospun shellac nanofibers with mupirocin using the Box-Behnken approach for topical wound care. Journal of Drug Delivery Science and Technology, 76(103720), 1-8. https://doi.org/10.1016/j.jddst.2022.103720


Journal : Journal of Drug Delivery Science and Technology  / in Scopus


ฐานข้อมูลงานวิจัย มหาวิทยาลัยสยาม  :  https://e-research.siam.edu/kb/designing-electrospun-shellac/

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The-Asian-Journal-of-Pharmaceutical-Sciencesvol13no5sep2018

Determination of mono-, di-, and trilaurin in modified coconut oil using HPLC–ELSD (2016)

 

Abstract

Modified coconut oil (MCO) enriched with monolaurin (ML) was prepared by the glycerolysis of coconut oil [1]. Glycerolysis converts dilaurin (DL) and trilaurin (TL) into ML, the lauric acidmonoglyceride. ML has been found to have antiviral, antibacterial and antifungal activities[2]. According to the antimicrobial activity, the glyceride composition of MCO was determined. The concentrations of ML, DL, and TL in MCO were analyzed using high-performance liquid chromatography–evaporative light scattering detector (HPLC–ELSD).

The HPLC–ELSD analyses were performed using an HPLC 1200 series equipped with an ELSD and a ZORBAX Eclipse Plus C18 column (4.6 × 250 mm, 5 µm) from Agilent Technologies Inc. The mobile phase consisted of 0.01% (v/v) acetic acid in acetonitrile(solvent A) and acetone (solvent B) and was degassed by ultrasonic bath prior to use. The HPLC column temperature was 25 °C. The mobile phase was maintained at a flow rate of 1.0 ml/min with the following gradient condition: solvent A:solvent B (90:10 v/v) from 0 to 5 min to solvent A:solvent B (70:30 v/v) from 5 to 10 min to solvent A:solvent B (50:50 v/v) from 10 to 15 min to solvent A:solvent B (30:70 v/v) from 15 to 20 min to solvent A:solvent B (20:80 v/v), and then held for 10 min. The equilibration time between runs was 10 min and the injection volume used was 10 µl. The temperature of the nebulization was set at 40 °C and nitrogen gas was 3.5 bar.

The ELSD were capable of a linear response (R2 > 0.9995) independent of individual glyceride molecular structures at concentrations between ~0.02 and 0.40 mg/ml. Intra- and inter-day reproducibility (n = 5) were evaluated under the optimized conditions. The relative standard deviations for glycerides were less than 2.45%. The detection limits (LODs) and the quantification limits (LOQs) were lower than 0.054 and 0.162 mg/ml, respectively. The efficiency of this method, measured through the recoveries, was higher than 96.06%. The elution order of the standards was ML < DL < TL as shown in Fig. 1. The DL and TL standards eluted after the ML standard, indicating that the hydroxyl moiety on the glycerol backbone contributed significantly to retention. The concentrations of ML, DL, and TL of MCO derived from various conditions of glycerolysis were in the ranges of 102.70–247.25 mg/ml (ML), 52.65–79.87 mg/ml (DL), and 12.27–39.60 mg/ml (TL).

Keywords: Monolaurin, Dilaurin, Trilaurin, Modified coconut oil, HPLC–ELSD

Link to Publication:  https://www.sciencedirect.com/science/article/pii/S1818087615001889

Bibliography  : Juthaporn Ponphaiboon, Sirikarn Pengon, Amornrat Chaidedgumjorn, Sontaya Limmatvapirat and Chutima Limmatvapirat.  (2016). Determination of mono-, di-, and trilaurin in modified coconut oil using HPLC–ELSD. Asian Journal of Pharmaceutical Sciences, 11(1), 223-224. (conference abstract).


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