Effect of needle sizes 30 G and 32 G on skin penetration force in cadavers: Implications for pain perception and needle change during botulinum toxin injections (2021)
Title : Effect of needle sizes 30 G and 32 G on skin penetration force in cadavers: Implications for pain perception and needle change during botulinum toxin injections
Researcher : Tansatit, T., Uruwan, S., Wilkes, M., Rungsawang, C.
Abstract : Cosmetic botulinum toxin injections usually cause discomfort to the patient. Using a small needle causes less pain compared to using a large needle,1 but a drawback is the price. A 30-G needle costs 2 THB while a 32-G needle costs 15 THB. The physician must decide when a needle is to be discarded. In one study, a 30-G needle was changed after approximately four to six punctures because of increased skin resistance.2 A 32-G needle is less painful than a 30-G needle because of the 25 percent smaller diameter of the 32-G needle.3 Instead of relying on individual tactile sense, we compared the penetration forces of two needle sizes to decide when to change the needle during botulinum toxin treatment.
Link to Academic article: DOI: 10.1097/PRS.0000000000008558
Journal : ,
Bibliography : Tansatit, T., Uruwan, S., Wilkes, M., & Rungsawang, C. (2021). Effect of needle sizes 30 G and 32 G on skin penetration force in cadavers: Implications for pain perception and needle change during botulinum toxin injections.
Effect of vitamin D on lung function assessed by forced oscillation technique in asthmatic children with vitamin D deficiency: A randomized double-blind placebo-controlled trial (2019)
Title : Effect of vitamin D on lung function assessed by forced oscillation technique in asthmatic children with vitamin D deficiency: A randomized double-blind placebo-controlled trial
Researcher : Clin.Prof.Suwat Benjaponpitak
Department : Faculty of Medicine, Siam University, Bangkok, Thailand
E-mail : med@siam.edu
Abstract : Background: The role of vitamin D and asthma in pulmonary function changes showed conflicting result.
Objective: To evaluate if vitamin D treatment would improve lung function assessed by forced oscillation technique (FOT) in vitamin D deficient asthmatic children.
Methods: A randomized double-blind placebo-controlled trial was performed in children, aged 3-18 years with well controlled asthma. Serum total 25(OH)D and FOT parameters including respiratory resistance at 5 Hz (R5), at 20 Hz (R20), respiratory reactance at 5 Hz (X5) and area of reactance (ALX), resonance frequency (Fres) were evaluated at baseline, 1 month and 3 months. Vitamin D deficient patients (serum total 25(OH)D < 20 ng/ml) were randomized to receive treatment with vitamin D2 (tVDD) or placebo (pVDD). Non-vitamin D deficient patients (nVDD) received placebo as a control group.
Results: A total of 84 children were recruited, 43 patients in nVDD group, 20 in tVDD group and 21 in pVDD group. There were no significant differences in age, sex, height and weight among groups. There were no significant differences of FOT parameters among groups at all visits. There was a trend toward decrease in R5/R20 from baseline to 1 month and 3 months visit in all groups, but the statistically significant improvement was observed only in nVDD group. Serum 25(OH)D showed no correlation with % predicted of FOT measures.
Conclusion: Vitamin D treatment in asthmatic children who had vitamin D deficiency may have no short term beneficial effect on pulmonary function assessed by FOT. Vitamin D supplementation in all asthmatic patient needs further study.
Link to Academic article: DOI: 10.12932/AP-010519-0553
Journal : Asian Pacific journal of allergy and immunology
Bibliography : Swangtrakul, N., Manuyakorn, W., Mahachoklertwattana, P., Kiewngam, P., Sasisakulporn, C., Jotikasthirapa, W., Kamchaisatian, W., & Benjaponpitak, S. (2019, December 14). Effect of vitamin D on lung function assessed by forced oscillation technique in asthmatic children with vitamin D deficiency: A randomized double-blind placebo-controlled trial. Asian Pac J Allergy Immunol, doi: 10.12932/AP-010519-0553. Epub ahead of print. PMID: 31837209.
Effectiveness and Adverse Events of Generic and Original Imipenem/Cilastatin in Hospitalized Patients: The First Multicenter Non-Inferiority Study in Thailand (2023)
Title : Effectiveness and Adverse Events of Generic and Original Imipenem/Cilastatin in Hospitalized Patients: The First Multicenter Non-Inferiority Study in Thailand
Researcher : Suankratay, C., Mootsikapun, P., Jirajariyavej, S., …Plongla, R.,Leelarasamee, A.
Department : Faculty of Medicine, Siam University, Bangkok, Thailand
Abstract : Objective: Imipenem/cilastatin, a broad-spectrum antibacterial, is reserved for treatment of serious infections caused by multidrug-resistant Gram-negative bacteria. The present study was aimed to compare the effectiveness and adverse events of generic and original imipenem/cilastatin.
Materials and Methods:A retrospective, multicenter, cohort, non-inferiority study of generic imipenem/cilastatin (Sianem®), and original imipenem/cilastatin (Tienam®) was carried on between November 2017 and September 2020. The centers included Srinagarind Hospital, Taksin Hospital, Nakornping Hospital, Nakhonpathom Hospital, and King Chulalongkorn Memorial Hospital. The clinically relevant data were retrieved from the medical records on day 3, 7, and 14 after enrollment. A sample size of 260 patients per arm was needed.
Results: There were 214 and 227 medical and surgical patients enrolled in generic and original imipenem/cilastatin groups, respectively. Baseline characteristics of the two groups were not significantly different. Most patients were male and elderly. Comorbidity was observed in 86.6%. The average length of hospital stay was 17 days. At day 14 after enrollment, the favorable outcome in generic and original imipenem/cilastatin groups were 83.1% and 90.0%, respectively, with no statistical difference. The mortality rates were 3.4% and 2.0% in generic and original imipenem/ cilastatin groups, respectively, with no statistic difference. Serious adverse events were also not significantly different between the two groups at 0.9% and 0.4%.
Conclusion: The generic imipenem/cilastatin was non-inferior to the original imipenem/cilastatin in terms of effectiveness and adverse events for the treatment of serious bacterial infections in hospitalized adult patients.
Keywords: Effectiveness; Safety; Adverse events; Generic drug; Imipenem/cilastatin
Link to article: Journal of the Medical Association of Thailand, 2023, 106(8), pp. 785–790. DOI: 10.35755/jmedassocthai.2023.08.13876
Bibliography : Suankratay C,Mootsikapun P, Jirajariyavej S,Kawila R, Nimitvilai S, Plongla R, & Leelarasamee A. (2023). Effectiveness and adverse events of generic and original imipenem/cilastatin in Hospitalized Patients: The first multicenter non-inferiority study in Thailand.
Effectiveness of modified health belief model-based intervention to reduce body mass index for age in overweight junior high school students in Thailand (2019)
Title : Effectiveness of modified health belief model-based intervention to reduce body mass index for age in overweight junior high school students in Thailand
Researcher : Waraporn Kamrot*, Arnond Vorayingyong, Siriluck Suppapitiporn, Thanapoom Rattananupong, Vitool Lohsoonthorn
Department : * Faculty of Nursing, Siam University, Bangkok, Thailand
E-mail : wara_aui@hotmail.com
Link to Published: Journal of Health Research
Bibliography : Khumros, W., Vorayingyong, A., Rattananupong, T., Suppapitipornand, S. & Lohsoonthorn, V. (2019). Effectiveness of Modified Health Belief Model-Based Intervention to Reduce Body Mass Index for Age in Overweight Junior High School Students in Thailand. Journal of Health Research, 33(2), 162-172.
Effectiveness of smoking cessation program applying the transtheoretical model among students of Siam University (2018)
Title : Effectiveness of smoking cessation program applying the transtheoretical model among students of Siam University
Researcher : Payungsak Jantrasurin1*, Duangkamol Viroonudomphol2* and Wattanee Panjinda2*
Department : 1* Department of Graduate School of Education Adminisstration and Leadership, Siam University, Bangkok, Thailand 2*Faculty of Nursing, Siam University, Bangkok, Thailand
E-mail : v_duangkamol@yahoo.com
Abstract : Purpose – The purpose of this study is to examine effectiveness of smoking cessation program applying the ranstheoretical model among students of Siam University. Design/methodology/approach- The one group pretest-posttest quasi experimental study was conducted among students of Siam University in January- February 2018. A total of 80 male undergraduate students participated in the study. 40 smokers male students were an experimental group and 40 of non smokers male were controls. The experimental group was participated in a smoking cessation program according to their stage readiness toward changing behaviors. They met for the transtheoretical model for group discussion and cessation counseling for 2 days. A self-administered questionnaire was used to collect data. Compare differences between mean scores before and after the experimentation by paired t-test. Findings – All of 80 student participants were male. At 4th week after receiving the transtheoretical model for group counseling, the experimental group had a significantly higher mean score for decision balance, self-efficacy, and smoking cessation behaviors than before the experimental (p<0.05). Originality/value – These study results especially smoking behavior before experimentation and the abnormal electrocardiogram of mokers re-emphasized the rising public health concern of tobacco use among younger boys. Therefore, if one can prevent or restrain adolescent from undesirable behaviors, this would contribute a great deal to the public health and society.
Keywords : Smoking, Cessation program, Siam University
Donwload PDF : Effectiveness of smoking cessation program applying the transtheoretical model among students of Siam University
Proceeding : The 3rd International Conference of Multidisciplinary Approaches on UN Sustainable Development Goals UNSDGs 2018, Bangkok, Thailand
Link to Proceeding: http://dept.npru.ac.th/unsdgs2018/
Bibliography : Payungsak Jantrasurin, Duangkamol Viroonudomphol & Wattanee Panjinda. (2018). Effectiveness of smoking cessation program applying the transtheoretical model among students of Siam University. In Proceeding The 3rd International Conference of Multidisciplinary Approaches on UN Sustainable Development Goals UNSDGs 2018 (p.79-83). Nakhon Pathom: Nakhon Pathom Rajabhat University.
Effects of astaxanthin from shrimp shell on oxidative stress and behavior in animal model of Alzheimer’s disease (2019)
Title : Effects of astaxanthin from shrimp shell on oxidative stress and behavior in animal model of Alzheimer’s disease
Researcher : Taksima, T., Chonpathompikunlert, P., Sroyraya, M., Hutamekalin, P., Limpawattana, M., & Klaypradit, W.
Department : สำนักอธิการบดี มหาวิทยาลัยสยาม
E-mail : maruj.lim@siam.edu
ฐานข้อมูลงานวิจัย มหาวิทยาลัยสยาม : –
Link to article: Marine Drugs, 2019, 17(11), 628. https://doi.org/10.3390/md17110628
Journal : Marine Drugs / in Scopus
Bibliography : Taksima, T., Chonpathompikunlert, P., Sroyraya, M., Hutamekalin, P., Limpawattana, M., & Klaypradit, W. (2019). Effects of Astaxanthin from Shrimp Shell on Oxidative Stress and Behavior in Animal Model of Alzheimer’s Disease. Marine Drugs, 17(11), 628. https://doi.org/10.3390/md17110628
Effects of coconut (Cocos nucifera L.) protein hydrolysates obtained from enzymatic hydrolysis on the stability and rheological properties of oil-in-water emulsions (2016)
Title : Effects of coconut (Cocos nucifera L.) protein hydrolysates obtained from enzymatic hydrolysis on the stability and rheological properties of oil-in-water emulsions
Researcher : Thaiphanit, S., Schleining, G., Anprung, P.,
Department : ภาควิชาเทคโนโลยีการอาหาร คณะวิทยาศาสตร์ มหาวิทยาลัยสยาม
E-mail : somruedee.tha@siam.edu
ฐานข้อมูลงานวิจัย มหาวิทยาลัยสยาม: –
Link to article: Food Hydrocolloids, 2016, 60, pp. 252–264. https://doi.org/10.1016/j.foodhyd.2016.03.035
Journal : Food Hydrocolloids / in Scopus
Bibliography : Thaiphanit, S., Schleining, G., & Anprung, P. (2016). Effects of coconut (Cocos nucifera L.) protein hydrolysates obtained from enzymatic hydrolysis on the stability and rheological properties of oil-in-water emulsions. Food Hydrocolloids, 60, 252–264. https://doi.org/10.1016/j.foodhyd.2016.03.035
Effects of educational and financial interventions on the quality of antibiotics use in community care clinics in Bangkok: An interrupted time-series analysis (2023)
Title : Effects of educational and financial interventions on the quality of antibiotics use in community care clinics in Bangkok: An interrupted time-series analysis(2023)
Researcher : ดร. ดารารัตน์ สำเร็จวิทย์ – Dr. Dararat Samretwit, Yupadee Sirisinsuk
ฐานข้อมูลงานวิจัย มหาวิทยาลัยสยาม : https://e-research.siam.edu/kb/effects-of-educational-and-financial-interventions/
Link to article: The Thai Journal of Pharmaceutical Sciences Vol 47, Issue 2, 2023 https://digital.car.chula.ac.th/tjps/vol47/iss2/10/
Journal : The Thai Journal of Pharmaceutical Sciences / TCI กลุ่มที่ : 1
Effects of pharmacist interventions on cardiovascular risk factors and outcomes: An umbrella review of meta-analysis of randomized controlled trials (2022)
Title : Effects of pharmacist interventions on cardiovascular risk factors and outcomes: An umbrella review of meta-analysis of randomized controlled trials
Researcher : Rattanavipanon, W., Chaiyasothi, T., Puchsaka, P., …Veettil, S.K., Chaiyakunapruk, N.
Abstract : Aims
To grade the evidence from published meta-analyses of randomized controlled trials (RCTs) that assessed effects of pharmacist intervention on cardiovascular risk factors and cardiovascular outcomes.
Methods
MEDLINE, Embase, and the Cochrane Library were searched from database inception to July 2021. Meta-analyses of RCTs were eligible. Quality of evidence were assessed by GRADE approach.
Results
From 9308 publications, 149 full-text articles were evaluated for eligibility, and 24 studies with 85 unique meta-analyses that assessed effects of pharmacist intervention on cardiovascular risk factors and cardiovascular outcomes were selected. Overall, 71.7% (61/85) of unique meta-analyses showed significant impacts of pharmacist intervention. For the quality of evidence, 63.4% of meta-analyses had large heterogeneity (I2 > 50%) while 1.2, 16.5, 32.9 and 49.4% of meta-analyses were graded as high, moderate, low and very low quality based on GRADE approach, respectively. Among meta-analyses with moderate quality, pharmacist interventions significantly mitigated risk factors (including 6/3 mmHg reduction of blood pressure, increased the rate of lipid control, glucose control and smoking cessation (pooled odds ratio, [95% confidence interval] 1.91 [1.55, 2.35], 3.11 [2.3, 4.3] and 2.3 [1.33, 3.97], respectively) and improved medication adherence (1.67 [1.38, 2.02]). Furthermore, pharmacist interventions significantly reduced all-cause mortality (0.72 [0.58, 0.89]) and improved quality of life in patients suffering from chronic heart failure.
Conclusion
This umbrella review found convincing evidence that pharmacist intervention can provide a wide range of benefits in cardiovascular disease management, ranging from risk factor control, improvement in medication adherence and, in some settings, reduction in morbidity and mortality.
Link to article: https://doi.org/10.1111/bcp.15279
Journal : ,
Bibliography : , , T.,, , R., , S., , S. K. N.(Effects of pharmacist interventions on cardiovascular risk factors and outcomes: An umbrella review of meta-analysis of randomized controlled trials. ,
Effects of scapulothoracic exercises on chest mobility, respiratory muscle strength, and pulmonary function in male COPD patients with forward shoulder posture: a randomized control trial (2022)
Title : Effects of scapulothoracic exercises on chest mobility, respiratory muscle strength, and pulmonary function in male COPD patients with forward shoulder posture: a randomized control trial
Researcher :
Department : Faculty of Medicine, Siam University, Bangkok, Thailand
E-mail : sarawut.lap@siam.ed
Link to article : F1000Research 2022, 11, 1284 https://doi.org/10.12688/f1000research.126832.1
Citation : Thongchote, K., Chinwaro, U., & Lapmanee, S. (2022). Effects of scapulothoracic exercises on chest mobility, respiratory muscle strength, and pulmonary function in male COPD patients with forward shoulder posture: a randomized control trial. F1000Research , 11, 1284. https://doi.org/10.12688/f1000research.126832.1
Journal : F1000Research / in Scopus
ฐานข้อมูลงานวิจัย มหาวิทยาลัยสยาม : –